IP Library › Granted Patent US 10,712,545
Granted Patent B2
US 10,712,545 · App. 15/904,916 · Granted Jul 14, 2020

Systems and methods for conducting contact-free thickness and refractive-index measurements of intraocular lenses using a self-calibrating dual confocal microscopy system

Inventors: Do-Hyun Kim (Clarksville, MD); Ilko Kolev Ilev (Rockville, MD); Robert Harold James (Gaithersburg, MD); Don Calogero (Montgomery Village, MD)
Assignee: The United States of America as represented by the Secretary, Department of Health and Human Services
G02B21/0032G01B11/06G01N21/41G02B21/02G02B21/06G02B21/18A61F2/16A61F2240/008G01N2021/4126
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Quick Facts
Patent No.
US 10,712,545
App. No.
15/904,916
Granted
Jul 14, 2020
Kind
B2
Abstract

Systems and methods for conducting contact-free thickness and refractive-index measurements of transparent objects, such as intraocular lenses using a dual confocal microscopy system are disclosed.

Claims (16)

1. A dual confocal microscopy system comprising:

a light source for transmitting a first laser beam;

a fiber optic coupler for splitting the first laser beam into a first divided laser beam and a second divided laser beam, the fiber optic coupler defining a first pathway for transmitting the first divided laser beam to the first confocal microscope and a second pathway for transmitting the second divided laser beam to the second confocal microscope;

a first confocal microscope in operative communication with the first pathway for receiving the first divided laser beam, the first confocal microscope comprising a first collimating lens for transforming the first divided laser beam into a plurality of first collimated laser beams and a first focusing lens having a first focal length for focusing the plurality of first collimated laser beams; and

a second confocal microscope in operative communication with the second pathway for receiving the second divided laser beam, the second confocal microscope comprising a second collimating lens for transforming the first divided laser beam into a plurality of second collimated laser beams and a second focusing lens having a second focal length for focusing the plurality of second collimated laser beams;

wherein the first confocal microscope and the second confocal microscope are longitudinally aligned along a beam axis as defined by the first pathway and the second pathway.

2. The microscopy system of claim 1 , further comprising:

a first object having predetermined thickness with a first reflective surface and an opposite second reflective surface, wherein the first object is positioned between the first confocal microscope and the second confocal microscope along the same beam axis.

3. The microscopy system of claim 2 , further comprising:

a detector in operative communication with the fiber optic coupler for detecting intensities of a plurality of signals generated by the first divided laser beam and the second divided laser beam detected by the detector.

4. The microscopy system of claim 2 , wherein the first reflective surface and the second reflective surface of the object are parallel to each other and are perpendicular to the beam axis.

5. The microscopy system of claim 2 , wherein the first confocal microscope detects the presence of the first reflective surface of the object and the second confocal microscope detects the presence of the second reflective surface in order to calculate the predetermined thickness of the object.

6. The microscopy system of claim 1 , wherein the laser source has a center wavelength at 658 nm.

7. The microscopy system of claim 1 , wherein the fiber optic coupler comprises a plurality of single mode fibers.

8. The microscopy system of claim 7 , wherein each of the plurality of single mode fibers has a diameter of approximately 5 μm.

9. The microscopy system of claim 1 , wherein the first and second collimating lenses are 10× objective lenses with an NA=0.25.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 10, 2018
From: KIM, DO-HYUN; ILEV, ILKO KOLEV; JAMES, ROBERT HAROLD; CALOGERO, DON
To: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
Reel/Frame 047124/0456 →
Continuity (2)
Provisional Application 62467849 · Mar 7, 2017
Related Publication 20180259759A1 · Sep 13, 2018