IP Library › Granted Patent US 10,716,544
Granted Patent B2
US 10,716,544 · App. 15/695,630 · Granted Jul 21, 2020

System for 3D multi-parametric ultrasound imaging

Inventors: Rajesh Venkataraman (Rocklin, CA); Saradwata Sakar (Newcastle, CA); Xu Yang (Nevada City, CA); Michael Ahmadi (Durham, NC); Pablo Medina (Grass Valley, CA)
Assignee: ZMK MEDICAL TECHNOLOGIES INC.
A61B8/5246A61B8/06A61B8/08A61B8/12A61B8/4218A61B8/4263A61B8/4461A61B8/463A61B8/469A61B8/481A61B8/485A61B8/488A61B8/5207A61B8/54G01S7/52042G01S7/52071G01S15/894G06T7/0012G01S7/52039G01S15/899G01S15/8993G06T2207/10136G06T2207/20081G06T2207/30081
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Quick Facts
Patent No.
US 10,716,544
App. No.
15/695,630
Granted
Jul 21, 2020
Kind
B2
Abstract

Systems and methods are disclosed that facilitate obtaining two dimensional (2D) ultrasound images, using two or more ultrasound imaging modes or modalities, to generate 2D multi-parametric ultrasound (mpUS) images and/or to generate a three-dimensional (3D) mpUS image. The different ultrasound imaging modes acquire images in a common frame of reference during a single procedure to facilitate their registration. The mpUS images (i.e., 2D or 3D) may be used for enhanced and/or automated detection of one or more suspicious regions. After identifying one or more suspicious regions, the mpUS images may be utilized with a real-time image to guide biopsy or therapy the region(s). All these processes may be performed in a single medical procedure.

Claims (27)

1. An ultrasound medical imaging system, comprising:

an ultrasound probe;

a positioning device having:

a linkage with at least two rigid arms, wherein one end of said linkage is a free end that is operative to move in three dimensions and wherein said free end is configured to be locked in a fixed position;

a rotational shaft interconnected to the free end of said linkage;

a rotary encoder configured to generate an angular outputs indicative of an angular orientation of said rotational shaft about said rotational axis;

a vibratory actuator for controllably imparting a vibration in said rotational shaft between a reference position and a displaced position, wherein said vibratory actuator moves said rotational shaft in a non-rotational direction; and

an ultrasound probe holder attached to said rotational shaft for releasable holding an acquisition array of the ultrasound probe in a known position relative to a rotational axis of said rotational shaft;

an ultrasound system for acquiring a plurality of two-dimensional ultrasound images in conjunction with rotation of said rotational shaft about said rotation axis and vibration of said rotational shaft, wherein each of said plurality of two-dimensional image are acquired while said rotational shaft is in said reference position;

a registration system configured to:

receive said angular outputs from said rotary encoder;

receive said plurality of two-dimensional ultrasound images; and

utilize said angular outputs to register said plurality of two-dimensional ultrasound images into a three-dimensional ultrasound image; and

a display configured to display said three-dimensional ultrasound image.

2. The system of claim 1 , wherein said vibratory actuator is configured to displace said rotational shaft in a direction substantially aligned with said rotational axis.

3. The system of claim 1 , further comprising:

a controller, the controller configured to:

control said vibratory actuator to displace said rotational shaft; and

operate said ultrasound to acquire an image while said rotational shaft is at said reference position.

4. The system of claim 1 , wherein said vibratory actuator vibrates said rotational shaft between said reference position and said displaced position at a user selectable frequency.

5. The system of claim 1 , wherein a distance between said reference position and said displaced position is user selectable.

6. The system of claim 1 , further comprising:

a motor for controllably rotating said rotational shaft.

7. The system of claim 6 , further comprising:

a controller configured to:

control said motor to rotate said rotational shaft to a known angular position; and

operate said ultrasound to acquire an image while said rotational shaft is in said known angular position.

Assignments (3)
MERGER Recorded Sep 18, 2020
From: ZMK MEDICAL TECHNOLOGIES, INC.
To: EIGEN HEALTH SERVICES, LLC
Reel/Frame 053815/0807 →
ASSET PURCHASE AGREEMENT Recorded Sep 11, 2020
From: ZMK MEDICAL TECHNOLOGIES, INC., A DELAWARE CORPORATION
To: ZMK MEDICAL TECHNOLOGIES, INC., A NEVADA CORPORATION
Reel/Frame 053754/0955 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 17, 2017
From: VENKATARAMAN, RAJESH; SAKAR, SARADWATA; YANG, XU; AHMADI, MICHAEL; MEDINA, PABLO
To: ZMK MEDICAL TECHNOLOGIES INC., DBA EIGEN, INC.
Reel/Frame 044161/0726 →
Continuity (3)
Continuation In Part 15289425 · Oct 10, 2016
Provisional Application 62238836 · Oct 8, 2015
Related Publication 20180008237A1 · Jan 11, 2018