IP Library › Granted Patent US 10,718,837
Granted Patent B2
US 10,718,837 · App. 15/493,842 · Granted Jul 21, 2020

3D UTE imaging using variable-TE stack-of-spirals acquisition

Inventors: John P. Mugler, III (Charlottesville, VA); Samuel W. Fielden (Lewisburg, PA); G. Wilson Miller, IV (Charlottesville, VA); Craig H. Meyer (Charlottesville, VA); Talissa A. Altes (Philadelphia, PA); Alto Stemmer (Erlangen, DE); Josef Pfeuffer (Erlangen, DE); Berthold Kiefer (Erlangen, DE)
Assignees: UNIVERSITY OF VIRGINIA PATENT FOUNDATION; SIEMENS HEALTHCARE GMBH
G01R33/4816A61B5/004A61B5/055A61B5/4504A61B5/4514A61B5/4523A61B5/4533A61B2576/02G01R33/4826
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Quick Facts
Patent No.
US 10,718,837
App. No.
15/493,842
Granted
Jul 21, 2020
Kind
B2
Abstract

Some aspects of the present disclosure relate to ultrashort-echo-time (UTE) imaging. In one embodiment, a method includes acquiring UTE imaging data associated with an area of interest of a subject. The acquiring comprises applying an imaging pulse sequence with a three-dimensional (3D) spiral acquisition and a nonselective excitation pulse. The method also includes reconstructing at least one image of the area of interest from the acquired UTE imaging data.

Claims (35)

1. A method for ultrashort-echo-time (UTE) imaging, comprising:

acquiring UTE imaging data associated with an area of interest of a subject, the acquiring comprising applying an imaging pulse sequence with a three-dimensional (3D) spiral acquisition and a nonselective excitation pulse; and

reconstructing at least one image of the area of interest from the acquired UTE imaging data.

2. The method of claim 1 , wherein the 3D spiral acquisition comprises a variable echo time (TE) 3D stack-of-spirals acquisition.

3. The method of claim 2 , wherein the 3D stack-of-spirals acquisition uses a 3D spoiled gradient-echo sequence.

4. The method of claim 2 , wherein the minimum TE is about 50 μs.

5. The method of claim 1 , wherein the nonselective excitation pulse is a nonselective hard RF excitation pulse.

6. The method of claim 1 , wherein the area of interest of the subject comprises an area of the musculoskeletal system of the subject.

7. The method of claim 1 , wherein the area of interest of the subject comprises the lungs of the subject.

8. The method of claim 1 , further comprising:

based on the reconstructed at least one image, determining at least one physiological characteristic of the area of interest of the subject.

9. A system for ultrashort-echo-time (UTE) imaging, comprising:

a data acquisition device configured to acquire UTE imaging data associated with an area of interest of a subject, the acquiring comprising applying an imaging pulse sequence with a three-dimensional (3D) spiral acquisition and a nonselective excitation pulse; and

one or more processors coupled to the data acquisition device and configured to cause the system to perform functions comprising:

reconstructing at least one image of the area of interest from the acquired UTE imaging data.

10. The system of claim 9 , wherein the data acquisition device comprises a magnetic resonance imaging device.

11. The system of claim 9 , wherein the 3D spiral acquisition comprises a variable echo time (TE) 3D stack-of-spirals acquisition.

12. The system of claim 11 , wherein the 3D stack-of-spirals acquisition uses a 3D spoiled gradient-echo sequence.

13. The system of claim 11 , wherein the minimum TE is about 50 μs.

14. The system of claim 9 , wherein the nonselective excitation pulse is a nonselective hard RF excitation pulse.

15. The system of claim 9 , wherein the area of interest of the subject comprises an area of the musculoskeletal system of the subject.

16. The system of claim 9 , wherein the area of interest of the subject comprises the lungs of the subject.

17. The system of claim 9 , wherein the one or more processors coupled to the data acquisition device are configured to cause the system to perform functions that further comprise:

based on the reconstructed at least one image, determining at least one physiological characteristic of the area of interest of the subject.

18. A non-transitory computer-readable medium having stored instructions that, when executed by one or more processors, cause one or more computing devices to perform functions that comprise:

acquiring UTE imaging data associated with an area of interest of a subject, the acquiring comprising applying an imaging pulse sequence with a three-dimensional (3D) spiral acquisition and a nonselective excitation pulse; and

reconstructing at least one image of the area of interest from the acquired UTE imaging data.

19. The non-transitory computer-readable medium of claim 18 , wherein the 3D spiral acquisition comprises a variable echo time (TE) 3D stack-of-spirals acquisition.

20. The non-transitory computer-readable medium of claim 19 , wherein the 3D stack-of-spirals acquisition uses a 3D spoiled gradient-echo sequence.

21. The non-transitory computer-readable medium of claim 19 , wherein the minimum TE is about 50 μs.

22. The non-transitory computer-readable medium of claim 18 , wherein the nonselective excitation pulse is a nonselective hard RF excitation pulse.

23. The non-transitory computer-readable medium of claim 18 , wherein the area of interest of the subject comprises an area of the musculoskeletal system of the subject.

24. The non-transitory computer-readable medium of claim 18 , wherein the area of interest of the subject comprises the lungs of the subject.

25. The non-transitory computer-readable medium of claim 18 , wherein the stored instructions, when executed by the one or more processors, cause the one or more computing devices to perform functions that further comprise:

based on the reconstructed at least one image, determining at least one physiological characteristic of the area of interest of the subject.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 066267/0346 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2020
From: STEMMER, ALTO; PFEUFFER, JOSEF; KIEFER, BERTHOLD
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 052177/0123 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 5, 2019
From: FIELDEN, SAMUEL W.; MUGLER, III, JOHN P.; MILLER, IV, GRADY WILSON; MEYER, CRAIG H.
To: UNIVERSITY OF VIRGINIA
Reel/Frame 051194/0867 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 5, 2019
From: ALTES, TALISSA A.
To: UNIVERSITY OF VIRGINIA
Reel/Frame 051194/0937 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 5, 2019
From: UNIVERSITY OF VIRGINIA
To: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Reel/Frame 051195/0015 →
Continuity (3)
Provisional Application 62335389 · May 12, 2016
Provisional Application 62325800 · Apr 21, 2016
Related Publication 20170307705A1 · Oct 26, 2017
Cited By (2)
US 12,716,972 US 12,730,171