IP Library › Granted Patent US 10,725,133
Granted Patent B2
US 10,725,133 · App. 15/481,749 · Granted Jul 28, 2020

Field-mapping and artifact correction in multispectral imaging

Inventors: Brady J. Quist (Stanford, CA); Brian A. Hargreaves (Menlo Park, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
G01R33/4833G01R33/243G01R33/5608G01R33/56563
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Quick Facts
Patent No.
US 10,725,133
App. No.
15/481,749
Granted
Jul 28, 2020
Kind
B2
Abstract

A method for generating a magnetic resonance image of an object in a magnetic resonance imaging (MRI) system, wherein the object contains at least one metallic implant is provided. The MRI system provides multiple excitations of at least part of the object. The MRI system reads out image signals from the object. The MRI system saves the readout image signals as image data. A field-map is generated from the image data using a goodness-of-fit process which uses a goodness-of-fit metric, matched-filter, and/or similar fitting techniques to fit expected signals from each excitation to the image data.

Claims (39)

1. A method for generating a magnetic resonance image of an object in a magnetic resonance imaging (MRI) system, wherein the object contains at least one metallic implant, comprising:

providing from the MRI system multiple excitations of at least part of the object;

reading out through the MRI system image signals from the object;

saving in the MRI system the readout image signals as image data;

generating a field-map from the image data using a goodness-of-fit process which uses a goodness-of-fit metric, matched-filter, and/or similar fitting techniques to fit expected signals using bin-specific displacements from each excitation to the image data;

generating a blurry or low-resolution image from the image data;

generating a deblurred or high-resolution image from the image data, using the field-map to deblur the image by using a spectral image combination that weights each image on a voxel by voxel basis based on a weighted noise reduction function, wherein the high-resolution image has a higher resolution than the low-resolution image;

generating a weighted image from the blurry image and deblurred image based on a goodness-of-fit; and

displaying the weighted image.

2. The method, as recited in claim 1 , wherein the goodness-of-fit process uses both a goodness-of-fit metric and a matched-filter to fit expected signals from each excitation to the image data.

3. The method, as recited in claim 2 , wherein the goodness-of-fit process comprises:

generating a matched-filter field-map; and

using the matched-filter field-map to generate a goodness-of-fit field-map.

4. The method, as recited in claim 3 , wherein the goodness-of-fit metric is used with a weighted-combination deblurring algorithm.

5. The method, as recited in claim 4 , wherein the weighted-combination deblurring algorithm is a weighted average deblurring algorithm.

6. The method, as recited in claim 5 , wherein the providing from the MRI system multiple excitations of at least part of the object provides multiple excitations of multiple spectral bins.

7. The method, as recited in claim 6 , wherein the weighted- image is a multispectral image.

8. The method, as recited in claim 1 , wherein the weighted noise reduction function provides a weighting based on expected contribution of each image voxel from the field-map.

9. The method, as recited in claim 8 , wherein the weighted image is a weighted average image.

10. The method, as recited in claim 1 , wherein the goodness-of-fit process uses both a goodness-of-fit metric and a matched-filter to fit expected signals from each excitation to the image data.

11. The method, as recited in claim 1 , wherein the goodness-of-fit process comprises:

generating a matched-filter field-map; and

using the matched-filter field-map to generate a goodness-of-fit field-map.

12. The method, as recited in claim 1 , wherein the goodness-of-fit metric is used with a weighted-combination deblurring algorithm.

13. The method, as recited in claim 12 , wherein the weighted-combination deblurring algorithm is a weighted average deblurring algorithm.

14. A method for generating a magnetic resonance image of an object in a magnetic resonance imaging (MRI) system, wherein the object contains at least one metallic implant, comprising:

providing from the MRI system multiple excitations of at least part of the object;

reading out through the MRI system image signals from the object;

saving in the MRI system the readout image signals as image data;

generating a field-map from the image data using a goodness-of-fit process which uses a goodness-of-fit metric and/or a matched-filter to fit expected signals using bin-specific displacements from each excitation to the image data;

generating a blurry image from the image data;

generating a deblurred image from the image data, using the field-map to deblur the image by using a spectral image combination that weights each image on a voxel by voxel basis based on an expected contribution of each image voxel from the field-map;

generating a weighted average image from the blurry image and deblurred image based on a goodness-of-fit; and

displaying the weighted average image.

15. The method, as recited in claim 14 , wherein the goodness-of-fit process uses both a goodness-of-fit metric and a matched-filter to fit expected signals from each excitation to the image data.

16. The method, as recited in claim 15 , wherein the goodness-of-fit process comprises:

generating a matched-filter field-map; and

using the matched-filter field-map to generate a goodness-of-fit field-map.

17. The method, as recited in claim 15 , wherein the goodness-of-fit metric is used with a weighted-average deblurring algorithm.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 7, 2017
From: QUIST, BRADY J.; HARGREAVES, BRIAN A.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 041929/0615 →
Continuity (2)
Provisional Application 62322053 · Apr 13, 2016
Related Publication 20170299682A1 · Oct 19, 2017