Tissue clip
A tissue clip for adjoining tissues including a body portion, a biasing mechanism interconnecting the body portion to a tissue grasping mechanism, the grasping mechanism having a first condition wherein the grasping mechanism is extending against and away from the body portion and a second condition wherein the grasping mechanism is biased against the body portion. A tissue clip and deployer combination. A method of interconnecting tissue by deploying the tissue clip, puncturing tissue to be interconnected with the tissue clip, and interconnecting the tissue. A method of treating an aneurism by deploying the tissue clip at an aneurism site, closing off the aneurism site with the tissue clip, and treating the aneurism. A method of imaging a surgical procedure with ultrasound by modifying a surface of a metal surgical instrument, and imaging the metal surgical instrument with ultrasound during a surgical procedure.
1. A tissue clip for adjoining tissues, the tissue clip comprising:
a body including at least one elongated body portion having a longitudinal axis, a front, and a back; and
at least two tissue grasping arms, each tissue grasping arm comprising an upper portion, an elongated straight portion, and a pointed end portion, wherein the upper portions of the two tissue grasping arms are connected to the body by a biasing mechanism such that the elongated straight portion of each tissue grasping arm is oriented in the same longitudinal direction as the longitudinal axis of the elongated body portion,
wherein the tissue grasping arms have a first condition in which the elongated straight portions of the tissue grasping arms are disposed away from and behind the back of the body and a second condition in which the elongated straight portions of the tissue grasping arms are rotated along their length and towards the front of the body, such that once deployed in tissue, the elongated straight portions of the tissue grasping arms are located in front of the body to both grasp and tuck the tissue to be joined, and wherein when the tissue clip is in the second condition, the tissue is tucked into a space between the tissue grasping arms and the front of the body.
2. The tissue clip of claim 1 , wherein the body is a shape chosen from the group consisting of a straight line, a loop, a circle, a triangle, a rectangle, and a tongue.
3. The tissue clip of claim 1 , wherein the tissue clip is formed of a biocompatible material.
4. The tissue clip of claim 3 , wherein the biocompatible material comprises one of, or a combination of two or more of, stainless steel, polymers, shape memory polymers, shape memory alloys, nitinol, titanium alloys, and cobalt alloys.
5. The tissue clip of claim 1 , wherein the tissue clip is made of a single piece of material and wherein the material comprises the biasing mechanism.
6. The tissue clip of claim 1 , wherein the clip is made of at least two pieces of material, such that the tissue grasping arms are attached to the body.
7. The tissue clip of claim 1 , wherein the tissue grasping arms include a coating.
8. The tissue clip of claim 7 , wherein the coating is an immunosuppressive coating.
9. The tissue clip of claim 8 , wherein the immunosuppressive coating comprises one of, or a combination of two or more of, protein kinase C inhibitors, glutamate receptor inhibitors, cyclosporins, FK506, corticosteroids, and ascomycins.
10. The tissue clip of claim 9 , wherein the coating is an imageable material.
11. The tissue clip of claim 8 , wherein the coating comprises one or both of polyurethane and polytetrafluoroethylene.
12. The tissue clip of claim 1 , wherein an exterior surface of the tissue clip includes physical modification.
13. The tissue clip of claim 12 , wherein the physical modification is a smooth coating on the tissue grasping arms.