Prevention of ventilator associated pneumonia (VAP)
Ventilator associated pneumonia (VAP) may be prevented in a patient, or its occurrence reduced in a population of patients, by using an anti-VAP device or an anti-VAP material such as an anti-VAP mouthpiece that absorbs secretions. By reducing the problem of bacterial-containing secretions that otherwise build up in the airway of, and elsewhere in, the intubated patient, VAP can be prevented from occurring in intubated patients, such as patients intubated with an endotracheal tube (ETT) or a nasogastric tube. Anti-VAP mouthpieces also are useable in non-intubated patients to maintain oral hygiene.
1. An anti-ventilator associated pneumonia (anti-VAP) mouthpiece device, comprising:
an upper segment;
a lower segment, wherein said upper segment and said lower segment are configured for arrangement in an oral cavity of a patient and form a barrier that blocks passage of VAP-causing secretions into a lower respiratory tract of said patient; and
an absorbent material forming at least part of either or both said upper segment and said lower segment, said absorbent material being configured to absorb VAP-causing secretions from at least said oral cavity of said patient,
wherein said upper segment and said lower segment define a center-hole configured to permit passage of an endotracheal tube (ETT) or a nasogastric tube and are configured so as not to obstruct a center pharyngeal lumen of said patient.
2. The anti-VAP mouthpiece device of claim 1 , wherein said upper segment and said lower segment are configured to conform to dental and proximal mucosal surfaces of said oral cavity of said patient.
3. The anti-VAP mouthpiece device of claim 1 , wherein said lower segment is configured to cover at least part of lower dentition and gingival of said patient.
4. The anti-VAP mouthpiece device of claim 1 , wherein said lower segment includes a lower plate configured to cover a tongue of said patient.
5. The anti-VAP mouthpiece device of claim 1 , wherein said upper segment is configured to cover at least part of upper dentition and gingival of said patient.
6. The anti-VAP mouthpiece device of claim 1 , wherein said upper segment includes an upper plate configured to cover a hard/soft palate surface of said patient.
7. The anti-VAP mouthpiece device of claim 1 , further comprising side wings configured to cover buccal mucosa of said patient.
8. The anti-VAP mouthpiece device of claim 7 , wherein said side wings are comprised at least partly of absorbent material.
9. The anti-VAP mouthpiece device of claim 7 , wherein the side wings have a first segment extending upwardly to cover an upper dental and mucosal region and a second segment extend downwardly to cover a lower dental and mucosal region.
10. The method anti-VAP mouthpiece device of claim 1 , wherein said absorbent material is saturated with antimicrobials or medicinals for sustained contact and releaskey Currently amended e to at least one dentition or mucosal surface of said patient.
11. The anti-VAP mouthpiece device of claim 1 , wherein said upper segment and said lower segment together form a solid member which is a one-size-fits-all shape installable in adult patients irrespective of tracheal diameter.
12. The anti-VAP mouthpiece device of claim 1 , wherein said upper segment and said lower segment together form a solid member which is a one-size-fits-all shape installable in pediatric patients irrespective of tracheal diameter.
13. The anti-VAP mouthpiece device of claim 1 , wherein the absorbent material comprises medicinals or antimicrobials.
14. The anti-VAP mouthpiece device of claim 13 , wherein said absorbent material is saturated with antimicrobials, and said antimicrobials are selected from the group consisting of chlorhexidine and hydrogen peroxide.
15. The anti-VAP mouthpiece device of claim 1 , wherein the absorbent material comprises an anesthetic agent.
16. The anti-VAP mouthpiece device of claim 1 , wherein the absorbent material has capacity to absorb at least 0.1 ml or 0.1 gm of secretions.
17. The anti-VAP mouthpiece device of claim 1 , wherein the absorbent material has capacity to absorb at least 1 ml or 1 gm of secretions.