Devices, systems, and methods for treating the left atrial appendage
Disclosed are embodiments of a method for occluding a left atrial appendage (LAA) and other cavities or openings within a body. Some embodiments of the method can include an implant configured to be deployed within the LAA or other cavity, configured to be expanded or moved against a wall portion of the LAA or other cavity, and configured to twist at least a portion of the LAA or other cavity when the implant is rotated. Thereafter, one or more securing elements, staples, sutures, or other fasteners can be implanted in the gathered tissue to hold the tissue in the gathered state, thereby occluding the opening of the LAA or other cavity. In some embodiments, the opening of the LAA or other cavity can be occluded by elongating or otherwise reshaping the opening using an implant device, and securing the opening in the occluded state.
1. A method of treating a left atrial appendage, comprising:
advancing a deployment device having an implant into the left atrial appendage, wherein the implant is configured to be moved from a first state to a second state, and wherein at least a portion of the implant is enlarged in a radial direction when the implant is in the second state as compared to the first state;
moving the implant from the first state to the second state within the left atrial appendage so as to move at least a portion of an outside surface of the implant or one or more tissue anchors extending away from an outer surface of the implant against an inner wall surface of the left atrial appendage;
rotating the implant from a first rotational position to a second rotational position to twist the left atrial appendage; and
preventing the implant from rotating back to the first rotational position.
2. The method of claim 1 , wherein the implant is self-expanding and wherein moving the implant from the first state to the second state comprises advancing the implant out of a distal end of the deployment device.
3. The method of claim 1 , wherein engaging a wall portion on an inside of the left atrial appendage comprises engaging a wall portion on an inside of the left atrial appendage with one or more tissue anchors positioned on an outside surface of the implant.
4. The method of claim 1 , wherein preventing the implant from rotating back to the first rotational position comprises engaging a tissue wall with an anchor element to prevent relative movement between the implant and the tissue wall.
5. The method of claim 1 , wherein preventing the implant from rotating back to the first rotational position comprises engaging a tissue wall with an anchor element, and wherein the anchor element is configured to be secured to the implant to prevent a rotation between the implant and the anchor element.
6. The method of claim 1 , wherein preventing the implant from rotating back to the first rotational position comprises engaging a tissue wall of the heart with an anchor element, wherein the anchor element is rotationally fixed relative to the implant and configured to prevent the implant from rotating back to the first rotational position.
7. The method of claim 1 , wherein preventing the implant from rotating back to the first rotational position comprises engaging a tissue of the heart outside of an occluded portion of the left atrial appendage with an anchor element, wherein the anchor element is rotationally fixed relative to the implant and configured to prevent the implant from rotating back to the first rotational position.
8. The method of claim 7 , wherein the anchor element comprises a plurality of tissue anchors on at least one surface thereof configured to engage with the internal wall of the heart outside of the left atrial appendage.
9. The method of claim 1 , wherein rotating the implant from the first rotational position to the second rotational position to twist the left atrial appendage comprises rotating the implant until an ostium of the LAA is substantially or completely closed.
10. The method of claim 1 , wherein rotating the implant from the first rotational position to the second rotational position to twist the left atrial appendage comprises rotating the implant at least approximately 90 degrees in either direction from the first rotational position.
11. The method of claim 1 , wherein rotating the implant from the first rotational position to the second rotational position to twist the left atrial appendage comprises rotating the implant at least approximately 180 degrees in either direction from the first rotational position.
12. The method of claim 1 , wherein rotating the implant from the first rotational position to the second rotational position to twist the left atrial appendage comprises rotating the implant from approximately 90 degrees to approximately 360 degrees in either direction from the first rotational position.
13. The method of claim 1 , wherein rotating the implant from the first rotational position to the second rotational position to twist the left atrial appendage comprises:
exerting a torque on the implant to rotate the implant in either direction from the first rotational position until a threshold predetermined torque level is reached;
holding the implant in the second rotational position; and
securing the implant in approximately the second rotational position relative to a tissue surface surrounding the left atrial appendage.
14. The method of claim 13 , wherein a maximum predetermined torque level is from approximately 0.25 in-oz of torque to approximately 10 in-oz of torque.
15. A method of treating a left atrial appendage, comprising:
advancing a deployment device having an implant into the left atrial appendage;
moving at least a portion of an outside surface of the implant or one or more tissue anchors extending away from an outer surface of the implant against an inner wall surface of the left atrial appendage;
rotating the implant from a first rotational position to a second rotational position to twist the left atrial appendage; and
preventing the implant from rotating back to the first rotational position.
16. The method of claim 15 , comprising moving at least a portion of an outside surface of the implant or one or more tissue anchors extending away from an outer surface of the implant against an inner wall surface of the left atrial appendage without changing a shape or size of the implant.
17. The method of claim 15 , further comprising moving the implant from a first state to a second state, and wherein at least a portion of the implant is enlarged in a radial direction when the implant is in the second state as compared to the first state.
18. A method of treating a left atrial appendage, comprising:
advancing a deployment device having an implant into the left atrial appendage;
engaging an inner wall surface of the left atrial appendage with the implant;
rotating the implant from a first rotational position to a second rotational position to twist the left atrial appendage; and
preventing the implant from rotating back to the first rotational position.
19. The method of claim 18 , comprising engaging an inner wall surface of the left atrial appendage with the implant without changing a shape or size of the implant.
20. The method of claim 18 , further comprising moving the implant from a first state to a second state, and wherein at least a portion of the implant is enlarged in a radial direction when the implant is in the second state as compared to the first state.