Vaginal laxity therapy utilizing cell-based bulking compositions
The invention provides methods for the treatment of vaginal laxity which include delivering a cell-containing composition to the vagina. The composition can include fat tissue to provide a bulking effect to reduce the size of the vaginal opening. The cells can provide healing and revascularization of the vaginal treatment area to sustain the bulking provided by the fat. The invention also provides systems and compositions useful for performing the method, and can include instruments and devices for removal of autologous adipose tissue from a patient (e.g., by liposuction), equipment for the enrichment of cells from adipose tissue, mechanical processing of adipose tissue, and the mixing of cells and processed adipose tissue. Devices for the delivery of the cell compositions to the vagina can also be included in the system.
1. A system for treating vaginal laxity, comprising:
an injection system configured to deliver a composition including adipose tissue cells to a vaginal cavity, the injection system including a balloon that includes an inner wall and an outer wall defining a space therebetween to contain the composition, the balloon including a first end portion and a second end portion and a middle portion between the first end portion and the second end portion, each of the first end portion, the middle portion, and the second end portion includes a plurality of openings to deliver the composition to the vaginal cavity, the injection system configured to reduce a size of the vaginal cavity in response to the delivery of the composition into the vaginal cavity,
the injection system including a tube connected to the balloon to supply the space of the balloon with the composition, a portion of the balloon including a hub member connected to a distal end of the tube.
2. The system of claim 1 , wherein the balloon comprises micro-needles.
3. The system of claim 1 , further comprising a member for providing the composition including adipose tissue cells of a patient.
4. The system of claim 3 , wherein the member comprises a device for enriching cells from the tissue sample.
5. The system of claim 3 , wherein the member comprises a device mechanically processing adipose tissue.
6. The system of claim 3 , wherein the member comprises a liposuction instrument.
7. The system of claim 1 , wherein the inner wall is void of a plurality of openings.
8. The system of claim 1 , wherein the space of the balloon is filled with at least one of a liquid or a gas to provide pressure to expand the outer wall of the balloon to a surface of the vaginal cavity.
9. The system of claim 1 , wherein the outer wall is constructed from a biocompatible material.
10. The system of claim 1 , wherein the outer wall is constructed from a non-absorbable material.
11. The system of claim 1 , wherein the outer wall is constructed from at least one of silicone rubber, nylon, polytetrafluoroethylene (PTFE), polyamide resin, polyesters, or organosiloxanes.