IP Library › Granted Patent US 10,792,305
Granted Patent B2
US 10,792,305 · App. 15/738,025 · Granted Oct 6, 2020

Therapeutic immune modulation using noble gas compositions

Inventors: Thomas Ichim (San Diego, CA); Vlad Bogin (Portland, OR)
Assignee: Nobilis Therapeutics, Inc.
A61K33/00A61K9/0073A61P25/28G01N33/6863
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Quick Facts
Patent No.
US 10,792,305
App. No.
15/738,025
Granted
Oct 6, 2020
Kind
B2
Abstract

Described are compositions of matter and protocols useful for treatment of neurological and other disorders associated with inflammatory activities. In some embodiments the invention provides means of modulating neuroinflammation through administration of noble gas containing compositions. In other aspects, the invention provides means of modulating stem cell compartments to enhance endogenous reparative activities or to synergize with existing treatments.

Claims (4)

1. A method of treating an autism spectrum disorder comprising the steps of: a) identifying a patient with an autism spectrum disorder; and b) administering a noble gas containing composition comprising oxygen and/or air and a proportion by volume of 20 to 70% of a noble gas at a sufficient concentration and frequency to a patient in need thereof to effectively treat said autism spectrum disorder.

2. The method of claim 1 , wherein said noble gas is xenon and/or a xenon donor.

3. The method of claim 1 , wherein said noble gas containing composition comprises a 25% xenon and a 75% air mixture by volume.

4. The method of claim 1 , wherein the noble gas is xenon gas and said administration is performed at a volume of 10 liters of the noble gas composition per administration, and at 3 administrations per week.

Continuity (3)
Provisional Application 62183624 · Jun 23, 2015
Provisional Application 62276753 · Jan 8, 2016
Related Publication 20180303871A1 · Oct 25, 2018