IP Library › Granted Patent US 10,793,883
Granted Patent B2
US 10,793,883 · App. 16/123,484 · Granted Oct 6, 2020

Engineered cyanobacteria with enhanced lipid production

Inventors: Viji Sitther (Pikesville, MD); Somayeh Gharaie Fathabad (Parkville, MD)
Assignee: Morgan State University
C12P7/649C07K14/195C12N1/20C12N9/0071C12N15/74C12P7/6463C12R1/01C12Y114/19
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,793,883
App. No.
16/123,484
Granted
Oct 6, 2020
Kind
B2
Abstract

A recombinant strain of F. diplosiphon was made by transforming wild type F. diplosiphon with a pGEM-7Zf (+) plasmid containing sterol desaturase gene (SD) via electroporation. The recombinant strain was designated B481-SD and overexpressed the sterol desaturase gene to result in enhanced lipid production. Selection made on NaCl enabled growth of the transformant to thrive up to 50 g L −1 NaCl. This strain was designated B481-SDH.

Claims (2)

1. A recombinant Fremyella diplosiphon cyanobacterium comprising at least one plasmid, said at least one plasmid including at least one polynucleotide having the sequence of SEQ ID NO: 1 which encodes a sterol desaturase polypeptide.

2. The recombinant Fremyella diplosiphon cyanobacterium according to claim 1 , having a higher salt tolerance as compared to wild-type Fremyella diplosiphon cyanobacterium.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 24, 2019
From: SITTHER, VIJI; FATHABAD, SOMAYEH GHARAIE
To: MORGAN STATE UNIVERSITY
Reel/Frame 050472/0757 →
Continuity (2)
Provisional Application 62555119 · Sep 7, 2017
Related Publication 20190071699A1 · Mar 7, 2019