IP Library › Granted Patent US 10,806,500
Granted Patent B2
US 10,806,500 · App. 16/233,951 · Granted Oct 20, 2020

Treatment systems, methods, and apparatuses for improving the appearance of skin and providing other treatments

Inventors: Leonard C. DeBenedictis (Dublin, CA); George Frangineas, Jr. (Fremont, CA); Kristine Tatsutani (Redwood City, CA); Linda Pham (Kensington, CA)
Assignee: Zeltiq Aesthetics, Inc.
A61B18/02A61B18/0206A61B90/04A61F7/00A61F7/007A61H1/006A61H1/008A61K31/045A61K31/047A61N7/00A61B2018/00291A61B2018/00464A61B2018/00714A61B2018/00791A61B2018/00875A61B2018/00994A61B2018/0237A61B2018/0262A61B2090/0463A61B2090/065A61F2007/0003A61F2007/0004A61F2007/0019A61F2007/0036A61F2007/0045A61F2007/0047A61F2007/0052A61F2007/0056A61F2007/0075A61F2007/0087A61F2007/0093A61F2007/0096
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Quick Facts
Patent No.
US 10,806,500
App. No.
16/233,951
Granted
Oct 20, 2020
Kind
B2
Abstract

Treatment systems, methods, and apparatuses for improving the appearance of skin or other target regions are described as well as for providing for other treatments. Aspects of the technology are directed to improving the appearance of skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite. Treatments can include cooling a surface of a patient's skin and detecting at least one freeze event in the cooled skin. The treatment system can continue cooling the patient's skin after the freeze event(s) are detected so to maintain at least a partially frozen state of the tissue for a period of time.

Claims (18)

1. A method for improving the appearance of skin, the method comprising:

cooling a surface of a patient's skin to a temperature no lower than about −40 degrees C. using a cooling device; and

controlling the cooling device to continue to cool the patient's skin for a period of time such that subcutaneous adipose tissue directy below the cooled patient's skin is not injured and such that dermal tissue of the skin is injured, via a cold -induced injury, to improve the appearance of the skin by tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, and/or improving the appearance of cellulite, and wherein the period of time being less than about 40 minutes, wherein the cooling device is controlled so that a most significant tissue injury cooling zone in the skin is centered between about 0.5 mm to about 2 mm deep.

2. The method of claim 1 , wherein the improvement in the appearance of skin does not include significant lightening or darkening of a color of the skin one or more days after a freeze event, which causes the dermal tissue to be injured, ends.

3. The method of claim 1 , further comprising applying sufficient cryoprotectant to the skin to protect epidermal tissue from freeze injury from the cooling device.

4. The method of claim 1 , further comprising supplying heat to the subcutaneous adipose tissue transcutaneously through the patient's skin.

5. The method of claim 1 , further comprising

cooling the skin sufficiently to cause a freezing event;

detecting the freezing event in the patient's skin; and

controlling the cooling device so that the freeze event lasts for no longer than a second period of time which is longer than about 10 seconds and shorter than 10 minutes.

6. The method of claim 1 , wherein the cooling device is controlled to cause skin tightening.

7. The method of claim 1 , wherein the cooling device is controlled to at least partially freeze tissue in the most significant tissue injury cooling zone which is within the dermal tissue.

8. The method of claim 1 , wherein the skin is facial skin.

9. The method of claim 1 , wherein the period of time is shorter than about 30 minutes.

10. A method for improving an appearance of skin, the method comprising: applying a cooling surface of a device to a surface of a patient's skin; and cooling the surface of the patient's skin to a temperature higher than about −40 degrees C. using the cooling surface to keep dermal tissue of the patient's skin within a cold injury temperature range for less than about 40 minutes and long enough to cause a cold injury in the dermal tissue of the patient's skin sufficient to produce the improved appearance of the skin by at least one of tightening the skin, improving skin tone or texture, eliminating or reducing wrinkles, increasing skin smoothness, or improving the appearance of cellulite, wherein the cold injury is centered between about 0.5 mm to about 2 mm deep so as to inhibit injury of subcutaneous adipose tissue directly below the cold injury.

11. The method of claim 10 , wherein the cold injury temperature range is below 0 degrees C.

12. The method of claim 10 , wherein the improved appearance of the skin is caused by the cold injury to the dermal tissue.

13. A method for altering a patient's skin, the method comprising: applying a cooling surface of a device to a surface of the patient's skin; and cooling the surface of the patient's skin to a temperature higher than about −40 degrees C. using the cooling surface to keep dermal tissue of the patient's skin within a cold injury temperature range for less than about 40 minutes but sufficiently long to cause a cold injury, which is centered at a depth of about 0.5 mm to about 2 mm, in the dermal tissue of the patient's skin, thereby inhibiting injury of subcutaneous adipose tissue directly below the cooled surface and causing an alteration to the appearance of the patient's skin by at least one of tightening the skin, improving skin tone and/or texture, eliminating or reducing wrinkles, increasing skin smoothness, or reducing the appearance of cellulite.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2018
From: DEBENEDICTIS, LEONARD C.; FRANGINEAS, GEORGE, JR.; PHAM, LINDA
To: ZELTIQ AESTHETICS, INC.
Reel/Frame 047876/0109 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 31, 2018
From: TATSUTANI, KRISTINE
To: ZELTIQ AESTHETICS, INC.
Reel/Frame 047876/0163 →
Continuity (5)
Division 14611127 · Jan 30, 2015
Provisional Application 61934549 · Jan 31, 2014
Provisional Application 61943250 · Feb 21, 2014
Provisional Application 61943257 · Feb 21, 2014
Related Publication 20190125424A1 · May 2, 2019
Cited By (5)
US 12,369,965 US 12,484,950 US 12,514,748 US 12,551,259 US 12,558,257