Medical device systems including an optical fiber with a tapered core

1. A medical device system, comprising:

a guidewire having a proximal end, the guidewire including a tubular member having a proximal region having a first wall thickness and a sensor region having a second wall thickness;

wherein the second wall thickness is thinner than the first wall thickness;

wherein the proximal region has a proximal outer diameter;

wherein the sensor region has a sensor region outer diameter;

wherein the proximal outer diameter is substantially equal to the sensor region outer diameter;

wherein the tubular member defines an inner lumen

wherein the inner lumen has a first diameter along the proximal region;

wherein the inner lumen has a second diameter larger than the first diameter along the sensor region;

an optical pressure sensor disposed within the inner lumen along the sensor region;

a connector cable coupled to the proximal end of the guidewire, the connector cable having a proximal end;

a signal conditioning unit coupled to the proximal end of the connector cable; and

wherein one or more of the guidewire, the connector cable, and the signal conditioning unit includes an optical fiber having a core with a tapered outer diameter.

2. The system of claim 1 , wherein the optical fiber having the core with the tapered outer diameter is disposed within the connector cable.

3. The system of claim 1 , wherein the optical fiber having the core with the tapered outer diameter is disposed within the signal conditioning unit.

4. The system of claim 1 , wherein the guidewire includes a second optical fiber that is coupled to the optical pressure sensor.

5. The system of claim 4 , wherein the optical fiber having the core with the tapered outer diameter is disposed within the connector cable and wherein the second optical fiber is coupled to the optical fiber having the core with the tapered outer diameter.

6. The system of claim 5 , wherein the optical fiber having the core with the tapered outer diameter is capable of receiving substantially all of a signal passing through the second optical fiber.

7. The system of claim 4 , wherein the optical fiber having the core with the tapered outer diameter is disposed within the signal conditioning unit, wherein the second optical fiber is coupled to a third optical fiber disposed within the connector cable, and wherein the third optical fiber is coupled to the optical fiber with the tapered core.

8. The system of claim 7 , wherein the optical fiber having the core with the tapered outer diameter is capable of receiving substantially all of a signal passing through the third optical fiber.

9. The system of claim 1 , wherein the connector cable includes a distal connector and wherein the connector cable is coupled to the proximal end of the guidewire at the distal connector.

10. The system of claim 1 , wherein the connector cable includes a proximal connector and wherein the signal conditioning unit is coupled to the proximal connector.

11. The system of claim 1 , wherein the tubular member has a plurality of slots formed therein.

12. The system of claim 1 , wherein the sensor region has an increased inner diameter.

13. A medical device system, comprising:

a guidewire including a tubular member having radially continuous tube wall, the guidewire comprising a proximal region where the tube wall has a first wall thickness and a sensor housing region where the tube wall has a second wall thickness;

wherein the proximal region of the tubular member has an outer diameter that is constant with an outer diameter of the sensor housing region;

an optical pressure sensor disposed within the sensor housing region, the optical pressure sensor having a first optical fiber extending therefrom;

a connector cable capable of being coupled to a proximal end of the guidewire, the connector cable including a second optical fiber that is capable of being coupled to the first optical fiber;

a signal conditioning unit capable of being coupled to the connector cable, the signal conditioning unit including a third optical fiber that is capable of being coupled to the second optical fiber; and

wherein at least one of the second optical fiber and the third optical fiber includes a core having at least a region with a tapered outer diameter.

14. The system of claim 13 , wherein the second optical fiber has the core having the region with the tapered outer diameter.

15. The system of claim 14 , wherein the second optical fiber is capable of receiving substantially all of a signal passing through the first optical fiber.

16. The system of claim 13 , wherein the third optical fiber has the core having the region with the tapered outer diameter.

17. The system of claim 16 , wherein the third optical fiber is capable of receiving substantially all of a signal passing through the second optical fiber.

18. A medical device system for determining fractional flow reserve, the system comprising:

a guidewire including a tubular member having a proximal region having a first wall thickness and a sensor housing region having a second wall thickness, the sensor housing region being disposed distally of the proximal region;

wherein the second wall thickness is thinner than the first wall thickness;

wherein the proximal region has a proximal outer diameter;

wherein the sensor housing region has a sensor housing outer diameter;

wherein the proximal outer diameter is substantially equal to the sensor housing outer diameter;

an optical pressure sensor disposed within the sensor housing region, the optical pressure sensor having a first optical fiber extending therefrom;

a connector cable capable of being coupled to a proximal end of the guidewire, the connector cable including a second optical fiber that is capable of being coupled to the first optical fiber;

wherein the second optical fiber includes a core having at least a region with a tapered outer diameter; and

a signal conditioning unit capable of being coupled to the connector cable, the signal conditioning unit including a third optical fiber that is capable of being coupled to the second optical fiber.

19. The medical device of claim 18 , wherein the second optical fiber is capable of receiving substantially all of a signal passing through the first optical fiber.