Leadless cardiac stimulation systems
Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Also disclosed are various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.
1. An implantable leadless cardiac pacing assembly, comprising:
a body having a proximal end region and a distal end region;
a first electrode positioned at the distal end region of the body;
a second electrode spaced proximally away from the first electrode on the body; and
a plurality of tines arranged radially around the first electrode, wherein each of the plurality of tines assumes a hooked configuration configured to anchor into tissue of a heart wall with the first electrode in contact with the tissue, wherein each of the plurality of tines includes a base, a distal tip and a curved region located between the base and the distal tip in the hooked configuration, wherein the curved region extends distal of the first electrode in the hooked configuration and the distal tip is located proximal of the first electrode in the hooked configuration.
2. The implantable leadless cardiac pacing assembly of claim 1 , wherein the curved region extends to a distalmost extent of the implantable leadless cardiac pacing assembly in the hooked configuration.
3. The implantable leadless cardiac pacing assembly of claim 1 , wherein the plurality of tines are circumferentially arranged around the distal end region of the body, wherein the plurality of tines are spaced substantially equidistant from one another.
4. The implantable leadless cardiac pacing assembly of claim 1 , wherein the distal tip of each of the plurality of tines points toward the body in the hooked configuration.
5. The implantable leadless cardiac pacing assembly of claim 1 , wherein the base of each of the tines is attached to a common junction member.
6. The implantable leadless cardiac pacing assembly of claim 1 , wherein the body has a cylindrical outer surface.
7. The implantable leadless cardiac pacing assembly of claim 6 , wherein the curved region of each of the tines extends radially outward of the cylindrical outer surface of the body in the hooked configuration.
8. The implantable leadless cardiac pacing assembly of claim 6 , wherein the second electrode extends around the cylindrical outer surface.
9. The implantable leadless cardiac pacing assembly of claim 1 , wherein the base of each of the tines is moveable relative to the body.
10. An implantable leadless cardiac pacing assembly, comprising:
a body having a proximal end region and a distal end region;
a power source contained within the body, the power source configured to be entirely implanted within a target region of a heart with the body;
a first electrode disposed at a distal end of the body and extending distally therefrom; and
a plurality of tines equidistantly spaced around the distal end region of the body, wherein each of the plurality of tines is in a hooked configuration in an equilibrium state;
wherein a distalmost extent of each of the plurality of tines is located distal of the first electrode in the hooked configuration; and
wherein a tip of each of the plurality of tines is located proximal of the distalmost extent of each of the plurality of tines in the hooked configuration.
11. The implantable leadless cardiac pacing assembly of claim 10 , wherein each of the plurality of tines includes a base at an end opposite from the tip, wherein the base of each of the plurality of tines is attached to a common junction member.
12. The implantable leadless cardiac pacing assembly of claim 10 , wherein each of the plurality of tines extends radially outward beyond the body in the hooked configuration.
13. The implantable leadless cardiac pacing assembly of claim 12 , wherein the distal tip of each of the plurality of tines points toward the body in the hooked configuration.
14. The implantable leadless cardiac pacing assembly of claim 10 , wherein each of the plurality of tines extends in a longitudinal orientation when deflected into a delivery configuration.
15. The implantable leadless cardiac pacing assembly of claim 14 , wherein the distal tip of each of the plurality of tines points toward a target tissue implantation site when in the delivery configuration.
16. An implantable leadless cardiac pacing assembly, comprising:
a cylindrical body having a proximal end region and a distal end region;
a power source contained within the body, the power source configured to be entirely implanted within a target region of a heart with the body;
a first electrode positioned at a distal end of the body and extending distally therefrom;
a second electrode spaced proximally away from the first electrode on the body; and
a plurality of tines equidistantly spaced around the distal end region;
wherein each of the plurality of tines includes a proximal base, a distal tip, and an intermediate region between the proximal base and the distal tip;
wherein the proximal base of each of the plurality of tines is attached to a common junction member;
wherein each of the plurality of tines is biased to have a hooked configuration when unconstrained; and
wherein the distal tip of each of the plurality of tines is located proximal of the intermediate region in the hooked configuration.
17. The implantable leadless cardiac pacing assembly of claim 16 , wherein each of the plurality of tines extends radially outward beyond the body in the hooked configuration.
18. The implantable leadless cardiac pacing assembly of claim 16 , wherein the distal tip of each of the plurality of tines points toward the body in the hooked configuration.
19. The implantable leadless cardiac pacing assembly of claim 16 , wherein the plurality of tines are arranged circumferentially around the first electrode.
20. The implantable leadless cardiac pacing assembly of claim 16 , wherein the proximal base of each of the tines is moveable relative to the body.