IP Library Granted Patent US 10,857,286
Granted Patent B2
US 10,857,286 · App. 16/081,202 · Granted Dec 8, 2020

System and method for improved fluid delivery in multi-fluid injector systems

Inventors: Michael Spohn (Fenelton, PA); Ralph Schriver (Tarentum, PA); Arthur E. Uber, III (Pittsburgh, PA); Ronald Heller (Monroeville, PA); Kevin Cowan (Allison Park, PA); Barry Tucker (Verona, PA); Edward Rhinehart (Murrysville, PA); Timothy Newing (Thornleigh, AU)
Assignee: BAYER HEALTHCARE LLC
A61M5/1408A61M5/007A61M5/14546A61M5/14566A61M2005/14208A61M2005/14553A61M2205/3331A61M2205/3334A61M2205/50
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Quick Facts
Patent No.
US 10,857,286
App. No.
16/081,202
Granted
Dec 8, 2020
Kind
B2
Abstract

A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel includes delivering at least a first fluid into the patient's blood vessel at a first flow rate, delivering at least a second fluid into the patient's blood vessel at a second flow rate, and adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

Claims (40)

1. A method of maintaining an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel, the method comprising:

delivering at least a first fluid into the patient's blood vessel at a first flow rate;

delivering at least a second fluid into the patient's blood vessel at a second flow rate; and

adjusting at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

2. The method of claim 1 , wherein adjusting at least one of the first flow profile of the first flow rate and a second flow profile of the second flow rate comprises delaying a delivery of one of the first fluid and the second fluid until the other of the first fluid and the second fluid reaches a predetermined flow rate.

3. The method of claim 1 , wherein adjusting at least one of the first flow profile of the first flow rate and a second flow profile of the second flow rate comprises adjusting one of the first flow rate and the second flow rate using a controller, wherein the adjusting is based on the other of the first flow rate and the second flow rate.

4. The method of claim 1 , further comprising pressurizing the first fluid using a first check valve to a first predetermined pressure before delivering the first fluid.

5. The method of claim 1 , further comprising pressurizing the second fluid using a second check valve to a second predetermined pressure before delivering the second fluid.

6. The method of claim 1 , further comprising pressurizing the first fluid and the second fluid using a first check valve and a second check valve to a first predetermined pressure and a second predetermined pressure, respectively, before delivering the first fluid and the second fluid.

7. The method of claim 1 , wherein adjusting at least one of the first flow profile of the first flow rate and a second flow profile of the second flow rate comprises over-delivering a predetermined volume of at least one of the first fluid and the second fluid during the delivery of the at least one of the first fluid and the second fluid.

8. The method of claim 1 , further comprising diluting one of the first fluid and the second fluid with a predetermined volume of the other of the first fluid and the second fluid.

9. The method of claim 1 , further comprising:

providing a multi-fluid injection system comprising:

a first syringe for receiving the first fluid and a first plunger movable within a barrel of the first syringe to pressurize the first fluid for delivery to the patient's blood vessel; and

a second syringe for receiving the second fluid and a second plunger movable within a barrel of the second syringe to pressurize the second fluid for delivery to the patient's blood vessel; and

reducing a capacitance of at least one of the first syringe and the second syringe to prevent backflow of at least one of the second fluid into the first syringe and the first fluid into the second syringe.

10. The method of claim 9 , further comprising providing a pressure jacket around an outer circumference of at least one of the first syringe and the second syringe to reduce the capacitance of the at least one of the first syringe and the second syringe when the at least one of the first syringe and the second syringe is under pressure.

11. The method of claim 1 , further comprising:

providing a multi-fluid injection system comprising:

a first syringe for receiving the first fluid and a first plunger movable within a barrel of the first syringe to pressurize the first fluid for delivery to the patient's blood vessel; and

a second syringe for receiving the second fluid and a second plunger movable within a barrel of the second syringe to pressurize the second fluid for delivery to the patient's blood vessel,

wherein at least one of the first syringe and the second syringe includes a reduced inner diameter to correspond to a desired flow rate.

12. The method of claim 11 , further comprising providing an obstruction member within at least one of the first syringe and the second syringe to reduce the inner diameter of at least one of the first syringe and the second syringe.

13. The method of claim 1 , further comprising:

providing a multi-fluid injection system comprising:

a first syringe for receiving the first fluid and a first plunger movable within a barrel of the first syringe to pressurize the first fluid for delivery to the patient's blood vessel; and

a second syringe for receiving the second fluid and a second plunger movable within a barrel of the second syringe to pressurize the second fluid for delivery to the patient's blood vessel;

providing an external restriction member on an outer circumference of at least one of the first syringe and the second syringe; and

adjusting an inner diameter of the external restriction member to adjust a permitted swelling of the at least one of the first syringe and the second syringe.

14. The method of claim 1 , wherein adjusting at least one of the first flow profile of the first flow rate and a second flow profile of the second flow rate comprises controlling one of the first flow rate and the second flow rate using an equalizing flow valve based on the other of the first flow rate and the second flow rate.

15. The method of claim 1 , wherein adjusting at least one of the first flow profile of the first flow rate and a second flow profile of the second flow rate comprises adjusting at least one of the first flow rate and the second flow rate before delivery of at least one of the first fluid and the second fluid based on at least one of known operating fluid pressure and capacitance of a multi-fluid injection system used to deliver the first fluid and the second fluid.

16. The method of claim 1 , wherein adjusting at least one of the first flow profile of the first flow rate and a second flow profile of the second flow rate comprises increasing a transition time between delivering one of the first fluid and the second fluid and delivering the other of first fluid and the second fluid.

17. A multi-fluid injection system configured to maintain an overall flow rate during a sequential delivery of at least two fluids to a patient's blood vessel, the system comprising:

a processor configured to control the multi-fluid injection system to:

deliver at least a first fluid into the patient's blood vessel at a first flow rate;

deliver at least a second fluid into the patient's blood vessel at a second flow rate; and

adjust at least one of a first flow profile of the first flow rate and a second flow profile of the second flow rate to dampen a transient increase in the overall flow rate during a transition between delivering one of the first fluid and the second fluid to delivering the other of the first fluid and the second fluid.

18. The controller of claim 17 , wherein the processor is further configured to control the multi-fluid injection system to increase a transition time between delivering one of the first fluid and the second fluid and delivering the other of the first fluid and the second fluid.

19. The controller as claimed in claim 17 , wherein the processor is further configured to control the multi-fluid injection system to delay the delivery of one of the first fluid and the second fluid until the other of the first fluid and the second fluid reaches a predetermined flow rate.

20. The controller as claimed in claim 17 , wherein the processor is further configured to control the multi-fluid injection system to over-deliver a predetermined volume of at least one of the first fluid and the second fluid during delivery of the at least one of the first fluid and the second fluid.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 14, 2020
From: COWAN, KEVIN P; TUCKER, BARRY L.; RHINEHART, EDWARD J
To: BAYER HEALTHCARE LLC
Reel/Frame 053756/0308 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 14, 2020
From: NEWING, TIMOTHY
To: BAYER HEALTHCARE LLC
Reel/Frame 053756/0357 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 3, 2018
From: SPOHN, MICHAEL A.; UBER, ARTHUR, III; SCHRIVER, RALPH H.; HELLER, RONALD
To: BAYER HEALTHCARE LLC
Reel/Frame 047650/0406 →
Continuity (2)
Provisional Application 62303050 · Mar 3, 2016
Related Publication 20190083699A1 · Mar 21, 2019