Vaginal composition and use thereof
A use of isomaltulose in the preparation of a vaginal composition, wherein the amount of isomaltulose used is 0.05-20% (w/w). A vaginal composition contains 0.05-20% (w/w) of isomaltulose. The composition may be a health product, health care product, cleaning product, skin care product, deodorant, cosmetic, or disinfectant composition or a pharmaceutical composition. A non-therapeutic vaginal care method, a non-therapeutic vaginal cleaning method, a method for improving vaginal acidity, a method for promoting growth of Lactobacillus in the vagina, and a method for preventing and treating vaginal dysbacteriosis, especially bacterial vaginal diseases, these methods being implemented by administering the composition to women's vagina.
1. A vaginal composition, comprising:
(1) isomaltulose, and
(2) antibacterial agents comprising: propionic acid and/or sodium propionate, and dehydroacetic acid and/or sodium dehydroacetate,
wherein the content of the isomaltulose is 0.05 to 20.0% (w/w), and the content of the antibacterial agents is 0.05 to 2.5% (w/w) in total.
2. The composition according to claim 1 , wherein the content of the isomaltulose is 1.5 to 12.0% (w/w).
3. The composition according to claim 1 , wherein the composition further comprises 0.001 to 1.0% (w/w) in total of an estrogen and/or phytoestrogen.
4. The composition according to claim 3 , wherein the estrogen and/or phytoestrogen is selected from the group consisting of: stilboestrol, estradiol, estriol, daidzin, daidzein, genistin, genistein, glycitin, glycitein, biochanin A, coumestrol and formononetin, and a combination thereof.
5. The composition according to claim 1 , wherein the composition is formed as one of the following: non-therapeutic vaginal health products, vaginal commodities, vaginal health care products, vaginal care products, vaginal cosmetics, vaginal hygiene products, or vaginal cleaning products; therapeutic vaginal health products, vaginal medical devices, or vaginal medicines; or vaginal cleaning agents or nourishing agents, deodorants, antipruritic agents, fresheners, wetting agents, lubricating agents, disinfectants, antibacterial agents, topical microbicidal agents, microecological modulators, or microorganism regulating agents.
6. The composition according to claim 1 , wherein the composition further comprises one or more extracts and vitamins selected from the group consisting of 0.1 to 5.0% (w/w) of aloe extract, 0.1 to 5.0% (w/w) of lavender extract, 0.001 to 1.0% (w/w) of vitamin E, 0.001 to 1.0% (w/w) of vitamin A, 0.001 to 1.0% (w/w) of vitamin D, 0.001 to 1.0% (w/w) of vitamin C, or a combination thereof.
7. The composition according to claim 1 , wherein the composition is a non-flowable, viscous water-soluble gel, which further comprises: a non-flowable, viscous water-soluble gel matrix, wherein the gel matrix is xanthan gum or Carbomer,
wherein the content of the isomaltulose is 0.1 to 20% (w/v);
and the content of the antibacterial agents, in total, is 0.1 to 2.5% (w/v);
wherein the antibacterial agents further comprise one or more agents selected from a group consisting of benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, sodium sorbate, acetic acid, sodium acetate, diacetic acid, sodium diacetate, calcium propionate, caprylic acid, sodium caprylate, capric acid, sodium caprate, undecylenic acid, sodium undecylenate, lauric acid, sodium laurate, natamycin, lactoferrin, lactoferricin, and a combination thereof; and
wherein the pH value of the water-soluble gel is 3.5 to 6.0.
8. The composition according to claim 7 , wherein the content of the isomaltulose is 3.0 to 12.0% (w/v).
9. The composition according to claim 1 , wherein the composition is in vaginal dosage forms comprising: water-soluble gels, aqueous solutions, aerosols, creams, ointments, capsules, microcapsules, suppositories, effervescents, or tablets.