System and method for accurate estimation of intentional and unintentional leaks in flow generation systems
In one embodiment, a method for accurate leak estimation in a flow generation system includes measuring a total flow through the flow generation system, measuring a pressure in the primary flow circuit of the flow generation system, determining when the measured pressure is within a predetermined threshold of EPAP, and calculating an intentional leak flowrate and an unintentional leak flowrate based on the relationship Q FS (t)=Q IL (t)+Q UL (t) when the measured pressure is within the predetermined threshold. In another embodiment, a flow generation system includes in one embodiment an airflow generator connected in-line to a flow sensor, a pressure sensor and a patient interface connection by a first gas flow circuit, and a controller electrically coupled to the airflow generator, the flow sensor and the pressure sensor. The controller sends a control signal to the airflow generator based on a first flow value measured from the flow sensor and an unintentional leak flow value that is derived from a proportional relationship with an intentional leak flow value.
1. A method for accurate leak estimation in a flow generation system comprising:
measuring, with a flow sensor, a total flow through the flow generation system;
measuring, with a pressure sensor, a pressure in a primary flow circuit of the flow generation system (P PS (t));
determining when the measured P PS (t) indicates no breathing by determining when P PS (t) is within a predetermined threshold of EPAP indicating that P PS (t)≅EPAP, when P PS (t) is within 1 cmH 2 Q from EPAP; and
calculating an intentional leak flowrate and an unintentional leak flowrate based on the relationship Q FS (t)=Q IL (t)+Q UL (t) when the measured pressure is within the predetermined threshold.
2. The method of claim 1 , wherein the total flow includes a first flow source comprising ambient air and a second flow source comprising pressurized oxygen.
3. The method of claim 2 , the total flow includes a third flow source.
4. The method of claim 1 , wherein the primary flow circuit comprises the flow sensor for measuring the total flow, an airflow generator and a patient interface connection.
5. The method of claim 1 , wherein P PS (t)≅EPAP when P PS (t) is within 0.5 cmH 2 O from EPAP.
6. The method of claim 1 , wherein P PS (t)≅EPAP when P PS (t) is within 0.2 cmH 2 O from EPAP.
7. The method of claim 1 , wherein P PS (t)≅EPAP when P PS (t) is within 0.1 cmH 2 O from EPAP.
8. The method of claim 1 further comprising:
determining the intentional leak flow rate at least partially based on a selected patient interface orifice size.
9. The method of claim 1 further comprising:
determining a flowrate of the lungs Q IL (t) by satisfying the equations:
Q FS ( t )= Q IL ( p,t )+ Q UL ( p,t )+ Q L ( t )
when P PS ( t )≅EPAP,
Q FS ( t )= Q IL ( t )+ Q UL ( t ), and
Q UL ( p,t )=∝· Q IL ( p,t ).
10. The method of claim 1 further comprising:
determining a flowrate of the lungs Q IL (t) by satisfying the equations:
Q FS ( t )= Q IL ( p,t )+ Q UL ( p,t )+ Q L ( t )
when P PS ( t )≅EPAP, and
Q FS ( t )= Q IL ( t )+ Q UL ( t ).
11. The method of claim 1 further comprising modeling an orifice equation for a total leak using an empirical equation.