Using the light adjustable lens (LAL) to increase the depth of focus by inducing targeted amounts of asphericity
In general, the present invention relates to optical elements, which can be modified post-manufacture such that different versions of the element will have different optical properties. In particular, the present invention relates to lenses, such as intraocular lenses, which can be converted into aspheric lenses post-fabrication. Also, the present invention relates to a method for forming aspheric lenses post-fabrication.
1. An aspheric lens comprising:
a first polymer matrix; and
a modifying composition, dispersed in the first polymer matrix, and polymerized into a second polymer matrix interspersed within the first polymer matrix; wherein
the aspheric lens is not a multifocal lens, and
a wavefront of the aspheric lens at a 4 mm measurement aperture has a 4 th order spherical aberration in a range of (+0.194 μm, −0.385 μm).
2. The aspheric lens of claim 1 , wherein the first polymer matrix is one of a polyacrylate, a polymethacrylate, a polyvinyl, a polysiloxane, a polyphosphazenes and copolymers of thereof.
3. The aspheric lens of claim 2 , wherein the polysiloxane is a polydimethylsiloxane.
4. The aspheric lens of claim 3 , wherein the polydimethylsiloxane has at least one of the formulas:
wherein m, n, x and y each separately represents an integer having a value between 1 and 10,000.
5. The aspheric lens of claim 1 , wherein the first polymer matrix is formed in the presence of a crosslinker.
6. The aspheric lens of claim 5 , wherein the crosslinker has the formula:
wherein n represents an integer having a value between 1 and 10,000.
7. The aspheric lens of claim 1 , wherein the modifying composition has at least one of the formulas:
wherein n and x each separately represents an integer having a value between 1 and 10,000,
wherein n and x each separately represents an integer having a value between 1 and 10,000,
wherein m and n each separately represents an integer having a value between 1 and 10,000, and
wherein m, and n each separately represents an integer having a value between 1 and 10,000.
8. The aspheric lens of claim 7 , wherein the modifying composition has the formula
wherein n and x each separately represents an integer having a value between 1 and 10,000.
9. The aspheric lens of claim 2 , wherein the polyacrylate is one of a polyalkyl acrylates, a polyhydroxyalkyl acrylate and a combination thereof.
10. The aspheric lens of claim 2 , wherein the polymethacrylate is one of a polymethyl methacrylate, a polyhydroxyethyl methacrylate, a polyhydroxypropyl methacrylate and a mixture thereof.
11. The aspheric lens of claim 2 , wherein the polyvinyl is one of a polystyrene, a polyvinylpyrrolidone and mixtures thereof.
12. The aspheric lens of claim 1 , wherein:
the 4 th order spherical aberration of the wavefront of the aspheric lens is in the range of (−0.006 μm, −0.385 μm).
13. The aspheric lens of claim 1 , wherein:
the 4 th order spherical aberration of the wavefront of the aspheric lens is in the range of (0.194 μm, 0 μm).
14. The aspheric lens of claim 1 , wherein:
the aspheric lens, upon implantation into an eye, causes a total measured 4 th order spherical aberration over a 4 mm pupil in the eye in the range of (−0.10 μm, −0.23 μm).
15. The aspheric lens of claim 1 , wherein:
the aspheric lens, upon implantation into an eye, causes a total measured 4 th order spherical aberration over a 4 mm pupil in the eye in the range of (−0.04 μm, −0.10 μm).
16. The aspheric lens of claim 1 , wherein:
the 4 th order spherical aberration is a Z(12) type aberration.
17. The aspheric lens of claim 1 , wherein:
a defocus of the aspheric lens is −1 Dioptre.
18. The aspheric lens of claim 1 , wherein:
a magnitude of a 6 th order aberration of the wavefront of the aspheric lens at a 4 mm measurement aperture is smaller than 0.04 μm.
19. The aspheric lens of claim 18 , wherein:
the magnitude of the 6 th order aberration of the wavefront of the aspheric lens is smaller than 0.01 μm.
20. The aspheric lens of claim 1 , the modifying composition comprising:
one of a monomer and a macromer, with an endcap that includes a photopolymerizable group that facilitated the stimulus-induced polymerization.
21. The aspheric lens of claim 20 , comprising:
a photoinitiator that initiated a photopolymerization of the photopolymerizable group.
22. The aspheric lens of claim 1 , wherein:
the modifying compound is polymerized by stimulus-induced polymerization into a second polymer matrix.
23. The aspheric lens of claim 1 , wherein:
a 6 th order aberration of the wavefront of the aspheric lens at a 4 mm measurement aperture is in a range of (0 μm, 0.04 μm).
24. The aspheric lens of claim 1 , further comprising:
a photoinitiator.
25. The aspheric lens of claim 1 , the modifying composition comprising:
a group that was capable of photopolymerization before the modifying composition was polymerized.
26. The aspheric lens of claim 1 , wherein:
the 4 th order spherical aberration of the wavefront of the aspheric lens is in the range of (−0.106 μm, −0.385 μm).