IP Library Granted Patent US 10,898,733
Granted Patent B2
US 10,898,733 · App. 15/918,262 · Granted Jan 26, 2021

Beam shaping assembly for neutron capture therapy

Inventors: Yuan-Hao Liu (Jiangsu, CN); Wei-Lin Chen (Jiangsu, CN)
Assignee: NEUBORON MEDTECH LTD.
A61N5/1081A61N5/10A61N2005/109A61N2005/1095A61N2005/1098
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Quick Facts
Patent No.
US 10,898,733
App. No.
15/918,262
Granted
Jan 26, 2021
Kind
B2
Abstract

Abeam shaping assembly for neutron capture therapy includes a beam inlet, a target having nuclear reaction with an incident proton beam from the beam inlet to produce neutrons forming a neutron beam, a moderator adjoining to the target, a reflector surrounding the moderator. The neutrons are moderated to epithermal neutron energies by the moderator, and part of the moderator disposed on the back of the target can be replaced so as to adjust the epithermal neutron energies. The reflector leads the neutrons deviated from the main axis back.

Claims (35)

1. A beam shaping assembly for neutron capture therapy comprising:

a beam inlet;

a target, wherein the target has nuclear reaction with the incident proton beam from the beam inlet to produce neutrons;

a moderator adjoining to the target, wherein the neutrons are moderated by the moderator to epithermal neutron energies and the moderator is replaceable so as to adjust the epithermal neutron energies;

a reflector surrounding the moderator, wherein the reflector leads deflected neutrons back to enhance the epithermal neutron beam intensity; and

a beam outlet.

2. The beam shaping assembly for neutron capture therapy according to claim 1 , wherein the moderator comprises a base portion disposed on the back of the target and an expanding portion separated from the base portion, and wherein the expanding portion is replaceable independently to adjust the epithermal neutron energies.

3. The beam shaping assembly for neutron capture therapy according to claim 2 , wherein the base portion adjoins to the back of the target and is fixed to the target, and the expanding portion is arranged at the back of the base portion and adjoins to the base portion.

4. The beam shaping assembly for neutron capture therapy according to claim 2 , wherein the expanding portion at least comprises a first expanding portion disposed on the back of the base portion and adjoining to the base portion and a second expanding portion arranged at the back of the first expanding portion and adjoining to the first expanding portion, and at least one of the first expanding portion and the second expanding portion is replaceable independently.

5. The beam shaping assembly for neutron capture therapy according to claim 2 , wherein the reflector at least comprises a supplementary reflecting portion surrounding the expanding portion.

6. The beam shaping assembly for neutron capture therapy according to claim 5 , wherein both of the supplementary reflecting portion and the expanding portion are replaceable to adjust the epithermal neutron energies.

7. The beam shaping assembly for neutron capture therapy according to claim 6 , wherein the supplementary reflecting portion and the expanding portion are moved into the beam shaping assembly through a guide slot arranged on the reflector to adjust the epithermal neutron energies.

8. The beam shaping assembly for neutron capture therapy according to claim 6 , wherein the supplementary reflecting portion and the reflector surrounding the base portion co-reflect deflected neutrons.

9. The beam shaping assembly for neutron capture therapy according to claim 4 , wherein the reflector is provided with a guide slot for guiding the expanding portion into the beam shaping assembly and the guide slot is extending to the back of the base portion, the guide slot is provided with a slide rail, the expanding portion is amounted in the guide slot and moves along the slide rail, so as to adjoin to the back of the base portion; the guide slot at least comprises a first guide slot a second guide slot; when the first expanding portion and the second expanding portion are identical in structure size and different in material, the first expanding portion and the second expanding portion are installed in the first guide slot or the second guide slot respectively; and when the first expanding portion and the second expanding portion are different in structure size and different in material, the first expanding portion is installed in the first guide slot, and the second expanding portion is installed in the second guide slot.

10. The beam shaping assembly for neutron capture therapy according to claim 4 , wherein the materials of the base portion, the first expanding portion and the second expanding portion are made of at least one of Al, Pb, Ti, Bi, C, D 2 O, AlF 3 , CaF 2 , Li 2 CO 3 , MgF 2 and Al 2 O 3 , the reflector is made of at least one of Pb or Ni.

11. A beam shaping assembly for neutron capture therapy comprising:

a beam inlet;

a target, wherein the target has nuclear reaction with an incident proton beam from the beam inlet to produce neutrons;

a moderator adjoining to the target, wherein the neutrons are moderated by the moderator to epithermal neutron energies, and the moderator comprises a base portion fixed to the target and an expanding portion adjoining to the base portion, one of the base portion and the expanding portion is replaceable independently;

a reflector surrounding the moderator, wherein the reflector leads deflected neutrons back to enhance epithermal neutron beam intensity; and

a beam outlet.

12. The beam shaping assembly for neutron capture therapy according to claim 11 , wherein the expanding portion at least comprises a first expanding portion disposed on the back of the base portion and adjoining to the base portion and a second expanding portion arranged at the back of the first expanding portion and adjoining to the first expanding portion, and at least one of the first expanding portion and the second expanding portion is replaceable independently.

13. The beam shaping assembly for neutron capture therapy according to claim 11 , wherein the reflector at least comprises a supplementary reflecting portion surrounding the expanding portion.

14. The beam shaping assembly for neutron capture therapy according to claim 13 , wherein both of the supplementary reflecting portion and the expanding portion are replaceable to adjust the epithermal neutron energies.

15. The beam shaping assembly for neutron capture therapy according to claim 14 , wherein the supplementary reflecting portion and the expanding portion are moved into the beam shaping assembly through a guide slot arranged on the reflector to adjust the epithermal neutron energies.

16. The beam shaping assembly for neutron capture therapy according to claim 14 , wherein the supplementary reflecting portion and the reflector surrounding the base portion co-reflect deflected neutrons.

17. A beam shaping assembly for neutron capture therapy comprising:

a beam inlet;

a target, wherein the target has nuclear reaction with an incident proton beam from the beam inlet to produce neutrons;

a moderator adjoining to the target, wherein the neutrons are moderated by the moderator to epithermal neutron energies, the moderator comprises at least a expanding portion, the expanding portion is replaceable independently without changing the whole moderator;

a reflector surrounding the moderator, wherein the reflector leads deflected neutrons back to enhance epithermal neutron beam intensity; and

a beam outlet.

18. The beam shaping assembly for neutron capture therapy according to claim 17 , wherein the expanding portion at least comprises a first expanding portion adjoining to the target and a second expanding portion, the first expanding portion is near the target, the second expanding portion arranged at the back of the first expanding portion and adjoining to the first expanding portion, and at least one of the first expanding portion and the second expanding portion is replaceable independently.

19. The beam shaping assembly for neutron capture therapy according to claim 18 , wherein the moderator comprises a base portion fixed to the target, and the first expending portion is disposed on the back of the base portion.

20. The beam shaping assembly for neutron capture therapy according to claim 17 , wherein the expanding portion is made of at least one of Al, Pb, Ti, Bi, C, D 2 O, AlF 3 , CaF 2 , Li 2 CO 3 , MgF 2 and Al 2 O 3 .

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2018
From: LIU, YUAN-HAO; CHEN, WEI-LIN
To: NEUBORON MEDTECH LTD.
Reel/Frame 045557/0314 →
Priority Claims (2)
CN 2015 1 0643065 · Sep 30, 2015 · national
CN 2015 2 0770873 U · Sep 30, 2015 · national
Continuity (2)
Continuation PCTCN2016089731 · Jul 12, 2016
Related Publication 20180193673A1 · Jul 12, 2018
Cited By (5)
US 12,245,355 US 12,303,713 US 12,434,074 US 12,447,359 US 12,465,786