IP Library Granted Patent US 10,933,082
Granted Patent B2
US 10,933,082 · App. 16/148,775 · Granted Mar 2, 2021

Cannabinoid composition and method for treating pain

Inventors: Ramachandra Mukunda (Potomac, MD); Ranga Chelva Krishna (Englewood, NJ)
Assignee: India Globalization Capital, Inc.
A61K31/714A61K9/0014A61K31/05A61K31/352A61K36/185A61K47/44
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Quick Facts
Patent No.
US 10,933,082
App. No.
16/148,775
Granted
Mar 2, 2021
Kind
B2
Abstract

A combination of THC, CBD and Cobalamin (in a ratio of about 63%, 27% and 10%, respectively) is used with a topical carrier such as Shea butter cream to relieve pain. The THC and CBD mixture is extracted from a Cannabis indica dominant strain using high pressure and carbon dioxide (CO 2 ) as a solvent and comprises: Tetrahydrocannabinol “THC” (9-Tetrahydrocannabinol (delta-9 THC), 8-Tetrahydrocannabinol (Delta-8 THC) and 9-THC Acid), Cannabidiol “CBD”, Cannabinol “CBN”, Cannabichromene (“CBC), Cannabigerol (“CBG”), terpenoids and flavonoids. The Shea butter is an extract from the Shea nut from the Shea tree ( Vitellaria paradoxa ). The weight of THC, CBD and Cobalamin, excluding other ingredients in the Indica extract, is in the range of about 1.0% to 5% of the total weight of the Shea butter. The cream is applied to joints for indications such as Psoriatic Arthritis and Scleroderma. The mixture is absorbed through the skin and interacts with the peripheral nervous and immune systems via the A Delta and C nerve fibers and CB 2 skin receptors to provide relief from pain without psychotropic or other side effects normally associated with THC.

Claims (20)

1. Method for treating pain comprising administering to a patient in need thereof:

(i) tetrahydrocannabinol (THC) in an amount from about 50% to about 70% by weight,

(ii) cannabidiol (CBD) in an amount from about 20% to about 40% by weight,

(iii) cobalamin in an amount from about 5% to about 20% by weight, and

(iv) a carrier;

wherein each percentage amount of THC, CBD and cobalamin is based on total weight of THC, CBD and cobalamin.

2. Method of claim 1 wherein THC is used in an amount greater than CBD and cobalamin is used in an amount less than either of THC or CBD.

3. Method of claim 1 wherein THC is used in an amount greater than 50% by weight, CBD in an amount up to about 30% by weight and cobalamin in an amount up to about 20% by weight.

4. Method of claim 1 wherein THC and CBD are extracted from Cannabis sativa.

5. Method of claim 1 wherein THC and or CBD are synthetic.

6. Method of claim 1 wherein CBD is organic CBD also containing cannabinol (CBN), cannabichromene (CBC), cannabigerol (CBG), terpenoids and flavonoids.

7. Method of claim 1 wherein THC, CBD and cobalamin are administered separately.

8. Method of claim 1 wherein THC is in the amount of about 63% by weight, CBD is in the amount of about 27% by weight and cobalamin is in the amount of about 11% by weight.

9. Method of claim 1 wherein THC and CBD are extracted from Cannabis indica.

10. Method of claim 9 wherein THC and CBD are extracted in an oil dissolved in liquid CO 2 , then the oil is separated therefrom.

11. Method of claim 1 wherein CBD is extracted from hempseed oil.

12. Method of claim 1 wherein the carrier is Shea butter.

13. Method of claim 12 wherein total weight of THC, CBD and cobalamin is about 1.0% to 5% of Shea butter's weight.

14. Method of claim 1 wherein a topical cream of THC, CBD, cobalamin and carrier is applied to a joint of the patient for the pain of psoriatic arthritis, herpetic neuralgia, trigeminal neuralgia, reflex sympathetic dystrophy, complex regional pain syndrome, or scleroderma.

15. Method of claim 1 wherein a patch delivers THC, CBD, cobalamin and carrier to an affected joint or area of skin of the patient.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 22, 2020
From: MUKUNDA, RAMACHANDRA; KRISHNA, RANGA CHELVA
To: INDIA GLOBALIZATION CAPITAL, INC.
Reel/Frame 054137/0071 →
Continuity (3)
Division 15104554
Provisional Application 62050864 · Sep 16, 2014
Related Publication 20190030062A1 · Jan 31, 2019
Cited By (2)
US 12,465,589 US 12,491,200