IP Library Granted Patent US 10,940,134
Granted Patent B2
US 10,940,134 · App. 16/698,432 · Granted Mar 9, 2021

Bicyclic compound and use thereof for medical purposes

Inventors: Tohru Kambe (Osaka, JP); Toru Maruyama (Osaka, JP); Shinsaku Yamane (Osaka, JP); Satoshi Nakayama (Osaka, JP); Kousuke Tani (Osaka, JP)
Assignee: ONO PHARMACEUTICAL CO., LTD.
A61K31/335A61K9/0048A61K31/4427A61K31/558C07D313/06C07D401/06C07D405/06C07D407/12C07D417/04
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Quick Facts
Patent No.
US 10,940,134
App. No.
16/698,432
Granted
Mar 9, 2021
Kind
B2
Abstract

Since a compound represented by the general formula (I) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and, further, has no side effect on eyes such as ocular stimulating property (hyperemia, corneal clouding etc.), aqueous humor protein rise etc., it has high safety, and can be an excellent agent for preventing and/or treating glaucoma etc.

Claims (2)

1. A pharmaceutical composition comprising the compound of formula (I):

and a pharmaceutically acceptable solvent, wherein the composition is a parenteral solution.

Priority Claims (1)
JP JP2009-175246 · Jul 28, 2009 · national
Continuity (7)
Continuation 16229446 · Dec 21, 2018
Continuation 15852493 · Dec 22, 2017
Continuation 15180125 · Jun 13, 2016
Continuation 14587829 · Dec 31, 2014
Continuation 14081286 · Nov 15, 2013
Continuation 13384383
Related Publication 20200093781A1 · Mar 26, 2020
Cited By (1)
US 12,201,603