Methods and uses of biological tissues for various stent and other medical applications
Methods and uses of biological tissues for various stent and other medical applications. In an exemplary embodiment of a method of processing a tissue of the present disclosure, the method comprises the steps of acquiring a mammalian tissue comprising at least a portion of a pulmonary region tissue, selecting a sample of pulmonary region tissue from the at least a portion of a pulmonary region tissue, and fixing the sample of pulmonary region tissue using a fixative, resulting in a fixed sample. In at least one embodiment, the step of selecting a sample of pulmonary region tissue comprises selecting a sample of pulmonary ligament tissue from the mammalian tissue.
1. A product, comprising:
a frame configured to retain a mammalian tissue thereon; and
the mammalian tissue coupled to the frame;
wherein when the product is positioned within a mammalian luminal organ, fluid native to the mammalian luminal organ may pass through a lumen defined within the product;
wherein the mammalian tissue comprises mammalian pulmonary ligament; and
wherein the mammalian tissue is fixed.
2. The product of claim 1 , wherein the mammalian tissue is chemically fixed.
3. The product of claim 1 , wherein the mammalian tissue is fixed using a fixative selected from the group consisting of glutaraldehyde, formaldehyde, and glycerol.
4. The product of claim 1 , wherein the mammalian tissue is fixed using a fixative within a HEPES or phosphate buffer.
5. The product of claim 1 , wherein the mammalian tissue is fixed using a fixation procedure selected from the group consisting of aqueous fixation, cryo-preservation, and dry tissue fixation.
6. The product of claim 1 , wherein the mammalian tissue is fixed using a fixative that is buffered.
7. The product of claim 1 , wherein a segment of the mammalian tissue is decellularized.
8. The product of claim 1 , wherein the mammalian tissue is sterilized.
9. A product, comprising:
a frame configured to retain a mammalian tissue thereon; and
the mammalian tissue coupled to the frame;
wherein when the product is positioned within a mammalian luminal organ, fluid native to the mammalian luminal organ may pass through a lumen defined within the product;
wherein the product is configured as a stent valve;
wherein the mammalian tissue comprises pulmonary ligament; and
wherein the mammalian tissue is fixed.
10. The product of claim 9 , wherein the mammalian tissue is chemically fixed.
11. The product of claim 9 , wherein the mammalian tissue is fixed using a fixative selected from the group consisting of glutaraldehyde, formaldehyde, and glycerol.
12. The product of claim 9 , wherein a segment of the mammalian tissue is decellularized.