IP Library › Granted Patent US 10,954,221
Granted Patent B2
US 10,954,221 · App. 16/902,807 · Granted Mar 23, 2021

GLP-1R agonists and uses thereof

Inventors: Wenge Zhong (Thousand Oaks, CA); Wei Guo (Shanghai, CN)
Assignee: QILU REGOR THERAPEUTICS INC.
C07D405/14C07D417/14C07D471/04
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Quick Facts
Patent No.
US 10,954,221
App. No.
16/902,807
Granted
Mar 23, 2021
Kind
B2
Abstract

The present disclosure provides compounds of Formula (I) and pharmaceutical compositions thereof, for use in, e.g. treating type 2 diabetes mellitus, pre-diabetes, obesity, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, and cardiovascular disease.

Claims (6)

1. A compound or a pharmaceutically acceptable salt thereof; wherein the compound is represented by the following structure:

2. A compound or a pharmaceutically acceptable salt thereof; wherein the compound is represented by the following structure:

3. A pharmaceutical composition comprising a pharmaceutically acceptable excipient, and a compound represented by the following structure:

or a pharmaceutically acceptable salt thereof.

4. A pharmaceutical composition comprising a pharmaceutically acceptable excipient, and a compound represented by the following structure:

or a pharmaceutically acceptable salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2020
From: ZHONG, WENGE; GUO, WEI
To: QILU REGOR THERAPEUTICS INC.
Reel/Frame 052955/0152 →
Priority Claims (1)
WO PCT/CN2019/082381 · Apr 12, 2019 · international
Continuity (2)
Continuation PCTCN2020084203 · Apr 10, 2020
Related Publication 20200325121A1 · Oct 15, 2020
Cited By (6)
US 12,365,670 US 12,473,271 US 12,497,382 US 12,516,041 US 12,570,642 US 12,590,081