IP Library › Granted Patent US 10,959,979
Granted Patent B2
US 10,959,979 · App. 16/868,558 · Granted Mar 30, 2021

Small molecules against cancer

Inventors: Amnon Peled (Tel-Aviv, IL); Michal Abraham Karni (Mevasseret Zion, IL); Orly Eizenberg (Rechovot, IL)
Assignee: Biokine Therapeutics Ltd.
A61K31/352A61K31/167A61K31/192A61K31/341A61K31/366A61K31/37A61K31/661A61K45/06A61P35/00C07D215/26C07D311/76C07D401/12C07D405/12C07D471/04
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Quick Facts
Patent No.
US 10,959,979
App. No.
16/868,558
Granted
Mar 30, 2021
Kind
B2
Abstract

Compounds capable of, or usable in, killing cancer cells, and/or modulating a biological activity of a chemokine, and/or inhibiting a kinase, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or treating disease and disorders such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are listed in Tables 2, 4 and 5, and/or are represented by Formulae I, IV, V and VI, as defined in the specification. Methods utilizing these compounds are also provided.

Claims (4)

1. A method of treating age-related macular degeneration (AMD) in a subject in need thereof, the method comprising administering to the subject a compound represented by the Formula:

thereby treating the age-related macular degeneration (AMD).

2. The method of claim 1 , wherein the age-related macular degeneration (AMD) is atrophic, non-neovascular (aAMD).

3. The method of claim 1 , wherein the age-related macular degeneration (AMD) is neovascular.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 18, 2022
From: BIOKINE THERAPEUTICS LTD.
To: ALONBIO LTD.
Reel/Frame 059042/0439 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 3, 2020
From: PELED, AMNON; ABRAHAM KARNI, MICHAL; EIZENBERG, ORLY
To: BIOKINE THERAPEUTICS LTD.
Reel/Frame 053682/0209 →
Continuity (5)
Continuation 16063278
Provisional Application 62268568 · Dec 17, 2015
Provisional Application 62268575 · Dec 17, 2015
Provisional Application 62268579 · Dec 17, 2015
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