Amphiphilic polymer and manufacturing method thereof, use of amphiphilic polymer as contact lens material, contact lens material including amphiphilic polymer
An amphiphilic polymer, an amphiphilic polymer manufacturing method, use of an amphiphilic polymer as a contact lens material, and a contact lens material including the same are provided. The amphiphilic polymer includes amino-conjugated mono-HEMA (mHEMA-NH 2 ) and amphiphilic chitosan bonded to the same. The amphiphilic polymer manufacturing method includes providing a mHEMA-NH 2 , providing an amphiphilic chitosan, and bonding the mHEMA-NH 2 to the amphiphilic chitosan.
1. An amphiphilic polymer, comprising:
amino-conjugated mono-HEMA (mHEMA-NH 2 ); and
amphiphilic chitosan bonded to the mHEMA-NH 2 ,
wherein the amphiphilic polymer has having the following structure:
2. A contact lens material, comprising the amphiphilic polymer according to claim 1 .
3. An amphiphilic polymer manufacturing method for manufacturing the amphiphilic polymer of claim 1 , including:
(S 1000 ) providing amino-conjugated mono-HEMA (mHEMA-NH 2 );
(S 2000 ) providing amphiphilic chitosan; and
(S 3000 ) bonding the mHEMA-NH 2 to the amphiphilic chitosan.
4. The method according to claim 3 , comprising a step of reacting ethylene diamine, potassium carbonate, and mHEMA-4-toluenesulfonyl-grafted (mHEMA-Ts) to obtain the mHEMA-NH 2 .
5. The method according to claim 4 , comprising a step of reacting mHEMA with 4-toluenesulfonyl chloride (TsCl) to obtain the HEMA-4-toluenesulfonyl-grafted.
6. The method according to claim 5 , further comprising during reaction of the mHEMA with 4-toluenesulfonyl chloride, using 4-dimethylaminopyridine (DMAP) as a catalyst.
7. The method according to claim 3 , wherein the step S 3000 comprises using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) as a catalyst.
8. The method according to claim 3 , wherein the step S 3000 comprises using N-hydroxysuccinimide (NHS) as a catalyst.