LRH-1 modulators

1. A compound having the formula:

wherein

W 1 and W 2 are independently CH or N;

L 1 is C(O)NH—, —NHC(O)—,

or —NHC(NH)NH;

R 1 is

unsubstituted alkyl;

R 2 is unsubstituted tert-butyl;

R 3 is unsubstituted tert-butyl;

R 4 is —OR 22 ;

R 22 is hydrogen,

halogen, —CX 3 , —CHX 2 , —CH 2 X, —OCX 3 , —OCH 2 X, —OCHX 2 , —CN, —OH, —NH 2 , —COOH, —CONH 2 , —NO 2 , —SH, —SO 3 H, —SO 4 H, —SO 2 NH 2 , —NHNH 2 , —ONH 2 , —NHC═(O)NHNH 2 , —NHC═(O) NH 2 , —NHSO 2 H, —NHC═(O)H, —NHC(O)—OH, —NHOH, substituted or unsubstituted alkyl, substituted or unsubstituted heteroalkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl;

X is —Cl, —Br, —I, or —F;

wherein R 1 is not unsubstituted methyl or unsubstituted tert-butyl; and

wherein the compound does not have the formula

2. The compound of claim 1 , wherein

R 1 is unsubstituted C 1 -C 8 alkyl.

3. The compound of claim 1 , having the formula:

4. The compound of claim 1 , wherein R 1 is unsubstituted C 1 -C 6 alkyl.

5. The compound of claim 1 , wherein R 4 is —OH.

6. The compound of claim 1 , wherein R 1 is unsubstituted butyl, unsubstituted pentyl, or unsubstituted hexyl.

7. The compound of claim 1 , wherein R 1 is unsubstituted C 3 -C 5 alkyl.

8. The compound of claim 1 , wherein R 1 is unsubstituted n-butyl.

9. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable excipient.

10. The compound of claim 1 , having the formula