Antifungal solution and foot wipe
A treatment solution has an antifungal agent, an antifungal agent solvent, and a carrier fluid, wherein the treatment solution is essentially free of alcohol. A wipe has a substrate, a treatment solution impregnated into the substrate, the treatment solution including an antifungal agent, an antifungal agent solvent, and a carrier fluid, wherein the treatment solution has an alcohol content of 6 wt % or below of the total solution. A treatment solution, has an antifungal agent, an antifungal agent solvent, and a carrier fluid, wherein the treatment solution has an alcohol content of 6 wt % or below of the total solution.
1. A treatment solution, comprising:
an antifungal agent comprising a naphthyl thiocarbamate;
a carrier fluid; and
an antifungal agent solvent comprising a dioxolane solvent miscible with the carrier and having a log Kow with a range of −1 to 1 the dioxolane comprising one selected from the group selected from: 1,3-dioxolane, 4-Methyl-1,3-dioxolane, 2-methyl-1,3-dioxolane, (2-Methyl-1,3-dioxolane-4-yl) methanol, 1,3-Dioxepane, 1,3-Dioxolane-4-methanol, 5-Hydroxy-1,3-dioxane, Glycrol formal mixture (60:40) of 1,3-Dioxolane-4-methanol:5-Hydroxy-1,3-dioxane, 1,4-dioxane, 1,3-dioxolane-2-one, and mixtures thereof,
wherein the treatment solution has an alcohol content of 1 wt % or below of the total solution.
2. The treatment solution as claimed in claim 1 , wherein the antifungal agent comprises tolnaftate.
3. The treatment solution as claimed in claim 1 , wherein the antifungal agent is tolnaftate having a concentration of at least 1 wt % of the total solution, and the antifungal agent solvent is dioxolane having a concentration in the range of 2 wt % to 4 wt % of the total solution.
4. The treatment solution of claim 1 , wherein the treatment solution further includes at least one of: emollients, surfactants, essential oils, thickening agents, texturizers, preservatives, and exfoliants.
5. The treatment solution of claim 4 , wherein the treatment solution further includes at least one of peppermint and eucalyptus.
6. A treatment solution, comprising
an antifungal agent comprising a naphthyl thiocarbamate;
a carrier fluid; and
an antifungal agent solvent comprising a dioxolane solvent miscible with the carrier fluid and having a log Kow with a range of −1 to 1 the dioxolane comprising one selected from the group consisting of: 1,3-dioxolane, 4-Methyl-1,3-dioxolane, 2-methyl-1,3-dioxolane, (2-Methyl-1,3-dioxolane-4-yl) methanol, 1,3-Dioxepane, 1,3-Dioxolane-4-methanol, 5-Hydroxy-1,3-dioxane, Glycrol formal mixture (60:40) of 1,3-Dioxolane-4-methanol:5-Hydroxy-1,3-dioxane, 1,4-dioxane, 1,3-dioxolane-2-one, and mixtures thereof,
wherein the treatment solution has an alcohol content of 6 wt % or below of the total solution.
7. The treatment solution as claimed in claim 6 , wherein the treatment solution has an alcohol content of 5 wt % or below.
8. The treatment solution as claimed in claim 6 , wherein the treatment solution has an alcohol content of 4 wt % or below.
9. The treatment solution as claimed in claim 6 , wherein the treatment solution has an alcohol content of 3 wt % or below.
10. The treatment solution as claimed in claim 6 , wherein the treatment solution has an alcohol content of 2 wt % or below.
11. The treatment solution as claimed in claim 1 , wherein the antifungal agent is terbinafine hydrochloride having a concentration of at least 1 wt % of the total solution, and the dioxolane antifungal agent solvent has a concentration in the range of 2 wt % to 4 wt % of the total solution.
12. The treatment solution of claim 4 , wherein the treatment solution further includes at least one of peppermint and eucalyptus.