Cosmetic compositions comprising magnetosomes and uses thereof
The present invention relates to cosmetic and skin care compositions comprising magnetosomes. The invention also relates to methods for the treatment of diseases associated with increased proliferation or accumulation of differentiating keratinocytes.
1. A cosmetic method for skin care in a subject which comprises the topical administration to said subject of a composition comprising magnetic nanoparticles which are forming part of a magnetosome, wherein the nanoparticles are not subjected to a magnetic field after application, wherein the magnetosomes are isolated from a magnetotactic microorganism and wherein the percentage (w/w) of magnetic particles in the composition is from about 0.0001% to about 0.001%.
2. The cosmetic method according to claim 1 for the treatment of chronological aging, photoaging, the accumulation of lipofuscin or skin pigmentation disorders.
3. The cosmetic method according to claim 2 wherein the magnetotactic microorganism is a magnetotactic bacteria.
4. The cosmetic method according to claim 3 wherein the magnetotactic bacteria is selected from the group consisting of Magnetospirillum gryphiswaldense MSR-1 , Magnetospirillum magneticum AMB-1 , Magnetospirillum magnetotacticum MS-1 , Magnetospirillum magneticum strain MGT-1, magnetotactic coccus strain MC-1 , Desulfovibrio magneticus RS-1 and anaerobic vibrios strains MV-1, MV-2 and MV-4.
5. The cosmetic method according to claim 1 wherein the nanomagnetic particles have a diameter of from about 35 nm to 120 nm.
6. The cosmetic method according to claim 1 wherein the composition comprising magnetic particles further comprises at least one additional skin care agent.
7. The cosmetic method according to claim 6 wherein the additional skin care agent is selected from the group consisting of vitamin A, vitamin E and collagen.
8. The cosmetic method according to claim 1 wherein the cosmetically acceptable adjuvant is selected from the group consisting of fillers, UVA and/or UVB sunscreens, thixotropic agents, antioxidants, preserving agents, dyes, pigments, fragrances, thickeners, vitamins, hormones, moisturizers, wetting agents, anionic, nonionic or amphoteric polymers and dermatological active substances.