Method to treat pain through electrical stimulation of nerves
Methods of treating pain are disclosed, wherein a non-pulsed, low-frequency electrical current is applied to the nerve carrying the pain signals in order to suppress transmission of those signals. In desired embodiments, the current is applied in a direction transverse to the nerve axis. Such currents have been found not to induce motor-neuron recruitment, meaning these methods can treat pain without causing muscle spasm or other muscular responses. A cuff for applying such a current transverse to the nerve axis is also disclosed.
1. A nerve cuff configured to transmit a current transverse to a longitudinal axis of a nerve, the nerve cuff comprising:
a substrate comprising a strip of dielectric material and having a hinge portion;
an anode electrode embedded in or laminated to the substrate; and
a cathode electrode embedded in or laminated to the substrate
wherein the anode electrode and the cathode electrode are positioned on the substrate opposite one another with respect to the hinge portion of the substrate, and
wherein the substrate is configured to bend at the hinge portion to enclose a peripheral nerve with the anode electrode and the cathode electrode diametrically opposed to one another about the peripheral nerve at a location where the cuff is applied, and
wherein the nerve cuff is connected to a waveform generator configured to generate the current configured as a non-pulsed electrical waveform that exhibits a delayed rise time to inhibit transmission of pain signals through C-fibers in the peripheral nerve without substantially activating motor fibers and higher-sensory nerve fibers in the peripheral nerve.
2. The nerve cuff of claim 1 , wherein the anode electrode and the cathode electrode are substantially planar.
3. The nerve cuff of claim 1 , wherein the anode electrode and the cathode electrode comprise a metallic foil and the dielectric material comprises silicone.
4. The nerve cuff of claim 1 , wherein the anode electrode and the cathode electrode are recessed in the dielectric material so that edges of the anode electrode and the cathode electrode are embedded in the dielectric material.