IP Library › Granted Patent US 11,013,850
Granted Patent B2
US 11,013,850 · App. 15/830,870 · Granted May 25, 2021

Composite fluid separation

Inventors: Bruce W. Gibbs (Arvada, CO); Bruce Ellingboe (Littleton, CO); Jeffrey J. Blakeslee (Arvada, CO)
Assignee: Terumo BCT, Inc.
A61M1/3696A61M1/029A61M1/0209A61M1/3698A61M1/382B04B5/0442B04B13/00A61M2202/0415A61M2202/0427A61M2202/0439A61M2205/3365A61M2205/50B04B2005/0471
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,013,850
App. No.
15/830,870
Granted
May 25, 2021
Kind
B2
Abstract

Embodiments are described that include systems and methods for separating components of a composite fluid, e.g., whole blood. Some embodiments provide for processing a composite fluid by subjecting a volume of the fluid to a first centripetal acceleration for an initial separation, followed by a second centripetal acceleration for a second separation.

Claims (33)

1. A system for separating components of a composite fluid, the system comprising:

a centrifuge;

a plurality of separation units positioned in the centrifuge, each of the separation units comprising:

a first chamber comprising a first expressor;

a second chamber positioned closer to an axis of rotation than the first chamber, wherein the second chamber comprises a second expressor;

a third chamber;

a first valve controlling flow from the first chamber; and

a second valve controlling flow from the second chamber; and

a memory storing processor-executable instructions that, when said instructions are executed, perform a method comprising:

spinning the centrifuge at a first speed to separate at least a first component, a second component, and a third component of the composite fluid;

transferring a portion of the first component and the second component from the first chamber to the second chamber using the first expressor;

spinning the centrifuge at a second speed; and

transferring a second portion of the first component out of the second chamber; and

transferring a third portion of the first component out of the first chamber using the first expressor.

2. The system of claim 1 , wherein the transferring of the second portion of the first component out of the second chamber is performed using the second expressor.

3. The system of claim 1 , wherein the transfer of the second portion of the first component out of the second chamber is performed using centripetal acceleration.

4. The system of claim 1 , wherein the step of transferring a second portion of the first component out of the second chamber transfers the second portion of the first component from the second chamber to the third chamber.

5. The system of claim 1 , wherein the step of transferring a second portion of the first component out of the second chamber transfers the second portion of the first component from the second chamber back to the first chamber.

6. The system of any one of claim 1 , wherein the step of transferring a third portion of the first component out of the first chamber transfers the third portion of the first component from the first chamber to the third chamber.

7. The system of claim 1 , wherein the third chamber is closer to the axis of rotation than the second chamber.

8. The system of claim 1 , wherein the composite fluid comprises whole blood.

9. The system of claim 8 , wherein the first component comprises plasma and the second component comprises platelets.

10. The system of claim 9 , wherein the second speed is faster than the first speed.

11. A method for separating components of a composite fluid, the method comprising:

subjecting a volume of the composite fluid comprising a first component, a second component, and a third component to a first centripetal acceleration;

separating the volume of composite fluid into two parts;

transferring a first part comprising a portion of the first component and the second component from a first chamber by action of a first expressor connected to said first chamber to a second chamber;

subjecting the transferred first part to a second centripetal acceleration thereby separating the first and second components;

returning the first component out of the second chamber by action of a second expressor coupled to said second chamber back to the first chamber; and

transferring said returned first component and an additional portion of the first component out of the first chamber.

12. The method of claim 11 , wherein the transferring the returned first component and the additional portion of the first component out of the first chamber further comprises, transferring the returned first component and the additional portion from the first chamber to a third chamber.

13. The method of claim 11 , wherein, the second centripetal acceleration is greater than the first centripetal acceleration.

14. The method of claim 11 , wherein the composite fluid comprises whole blood.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 18, 2018
From: GIBBS, BRUCE W.; ELLINGBOE, BRUCE; BLAKESLEE, JEFFREY J.
To: TERUMO BCT, INC.
Reel/Frame 044659/0315 →
Continuity (2)
Provisional Application 62429332 · Dec 2, 2016
Related Publication 20180154067A1 · Jun 7, 2018
Cited By (1)
US 12,661,650