Syringe barrel for pre-filled syringe, syringe system, and pre-filled syringe
A syringe body for a prefilled syringe includes: a hollow body portion; a proximal-end opening portion provided at a proximal end portion of the body portion; and a distal-end nozzle provided at a distal end portion of the body portion. The body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer. The body portion has a thick body portion accounting for 80% or more of the body portion along an axial direction. A wall thickness of the thick body portion is 2.23 to 2.40 mm.
1. A syringe body for a prefilled syringe, the syringe body comprising:
a hollow body portion;
a proximal-end opening portion disposed at a proximal end portion of the body portion; and
a distal-end nozzle disposed at a distal end portion of the body portion;
wherein the body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer;
wherein the body portion includes a thick body portion accounting for 80% or more of the body portion along an axial direction;
wherein a nominal volume of the syringe body is in a range of 0.1 to 5 mL; and
wherein a wall thickness of the thick body portion is in a range of 2.23 to 2.40 mm.
2. The syringe body according to claim 1 , wherein:
a nominal volume of the syringe body is in a range of 0.1 to 0.5 mL.
3. The syringe body according to claim 1 , wherein:
an area of an outer circumferential surface of the body portion is in a range of 1300 to 1600 mm 2 .
4. The syringe body according to claim 2 , wherein:
an area of an outer circumferential surface of the body portion is in a range of 1300 to 1600 mm 2 .
5. A syringe system for a prefilled syringe, the syringe system comprising:
a syringe body comprising:
a hollow body portion,
a proximal-end opening portion disposed at a proximal end portion of the body portion, and
a distal-end nozzle disposed at a distal end portion of the body portion
wherein the body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer,
wherein a nominal volume of the syringe body is in a range of 0.1 to 5 mL, and
wherein a wall thickness of the body portion is a range of 2.23 to 2.40 mm;
a gasket that is slidably disposed in the body portion; and
a cap comprising a sealing portion sealing an opening portion of the distal-end nozzle.
6. The syringe system according to claim 5 , wherein:
a nominal volume of the syringe body is in a range of 0.1 to 0.5 mL.
7. The syringe system according to claim 5 , wherein
the gasket includes a gasket body, and a fluororesin disposed on an outer surface of the gasket body.
8. The syringe system according to claim 5 , wherein:
the sealing portion of the cap is made of butyl rubber.
9. A prefilled syringe comprising:
a syringe body comprising:
a hollow body portion
a proximal-end opening portion disposed at a proximal end portion of the body portion, and
a distal-end nozzle disposed at a distal end portion of the body portion,
wherein the body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer,
wherein a nominal volume of the syringe body is in a range of 0.1 to 5 mL, and
wherein a wall thickness of the body portion is in a range of 2.23 to 2.40 mm;
a gasket that is slidably disposed in the body portion;
a cap comprising a sealing portion sealing an opening portion of the distal-end nozzle; and
a drug solution that is filled in a filling space formed by the syringe body and the gasket;
wherein an outer surface of the syringe body is sterilized with a hydrogen peroxide or ethylene oxide gas.
10. The prefilled syringe according to claim 9 , wherein:
a nominal volume of the syringe body is in a range of 0.1 to 0.5 mL.
11. A prefilled syringe comprising:
a syringe body comprising:
a hollow body portion,
a proximal-end opening portion disposed at a proximal end portion of the body portion, and
a distal-end nozzle disposed at a distal end portion of the body portion,
wherein the body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer,
wherein a nominal volume of the syringe body is in a range of 0.1 to 5 mL, and
wherein a wall thickness of the body portion is in a range of 2.23 to 2.40 mm;
a gasket that is slidably disposed in the body portion;
a cap comprising a sealing portion sealing an opening portion of the distal-end nozzle; and
a drug solution filled in a filling space formed by the syringe body and the gasket;
wherein the outer surface of the syringe body is a surface that has been sterilized with a hydrogen peroxide or ethylene oxide gas.
12. The prefilled syringe according to claim 11 , wherein:
the drug solution is a medicine that contains an active ingredient comprising at least one of: a protein, a peptide, and/or a nucleic acid.
13. The prefilled syringe according to claim 12 , wherein:
a nominal volume of the syringe body is in a range of 0.1 to 0.5 mL.