IP Library › Granted Patent US 11,026,984
Granted Patent B2
US 11,026,984 · App. 15/564,748 · Granted Jun 8, 2021

Use of isothiocyanate derivatives as modulators of peripheral and neuropathic pain

Inventors: Paolo Morazzoni (Milan, IT); Renato Iori (Bologna, IT)
Assignee: Indena S.P.A.
A61K36/185A61K31/26A61K31/7024A61K31/7034A61P25/00A61P25/02
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,026,984
App. No.
15/564,748
Granted
Jun 8, 2021
Kind
B2
Abstract

The present invention relates to the use of glucomoringin (GMG) and of the corresponding isothiocyanate derivative glucomoringin des-thioglucoside (GMG-ITC) as modulators of peripheral pain with specific reference to that linked with diabetic peripheral neuropathy and chemotherapy-induced neuropathy.

Claims (5)

1. Method of treating oxaliplatin-induced neuropathy in a subject in need thereof, said method comprising

administering glucomoringin, or glucomoringin des-thioglucoside, or an extract of Moringa oleifera seeds containing glucomoringin and/or glucomoringin des-thioglucoside to said subject; and

treating said subject of said oxaliplatin-induced neuropathy.

2. A method according to claim 1 , comprising administering glucomoringin.

3. A method according to claim 1 , comprising administering glucomoringin des-thioglucoside.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2017
From: MORAZZONI, PAOLO; IORI, RENATO
To: INDENA S.P.A.
Reel/Frame 044708/0579 →
Priority Claims (1)
EP 15163185 · Apr 10, 2015 · regional
Continuity (1)
Related Publication 20180104293A1 · Apr 19, 2018