Use of a new stimulation design to treat neurological disorders
The method and system described herein relate to stimulating nerve tissue using a pulse generator. A stimulus is created that comprises a signal that is produced from a frequency spectrum having a power spectral density per unit of bandwidth proportional to 1/f β , wherein β is excludes 0. The stimulus is provided from the pulse generator to at least one stimulation lead; and applied to nerve tissue via one or several electrodes.
1. An implantable pulse generator (IPG) for neurostimulation of a patient, comprising:
a battery for powering the IPG;
a processor for controlling the IPG according to executable instructions;
memory for storing executable instructions and data; and pulse generating circuitry for generating electrical pulses for stimulation of nerve tissue of the patient;
wherein (1) the processor controls pulse generation operations of the IPG according to one or more stimulation programs defined by a clinician of the patient, (2) IPG is programmable by the clinician to select from multiple stimulation patterns for pulse generation including a noise stimulation pattern, (3) the IPG is programmed to retrieve a parameter β from a respective stimulation program defined for the noise stimulation pattern to generate electrical pulses generally exhibiting amplitude variations for a noise power density profile of 1/f ∧ β where f represents frequency, and (4) the parameter β for the respective stimulation program is selectable by the clinician from a range of values including β=1, β=2, and multiple values therebetween.
2. The IPG of claim 1 wherein the IPG is programmed to apply a first stimulation program during an active state of the patient and is programmed to apply a second stimulation program during a sleep state of the patient, wherein the first stimulation program and the second stimulation program include different β values for respective noise stimulation patterns.
3. The IPG of claim 1 wherein the IPG is programmed to retrieve a second parameter from a respective stimulation program defined for the noise stimulation pattern to generate electrical pulses such that a noise power density profile of the respective stimulation program exhibits a peak at a frequency defined by the second parameter.
4. The IPG of claim 3 wherein the IPG is adapted to communicate with an external controller device to receive a value for the second parameter, wherein the external controller device measures neurological signals of the patient to select the value for the second parameter.
5. The IPG of claim 4 wherein the neurological signals are EGG signals.
6. The IPG of claim 1 wherein the multiple stimulation patterns includes burst stimulation, wherein burst stimulation includes a plurality of groups of multiple pulses with adjacent groups being separated by respective quiescent periods.
7. The IPG of claim 1 wherein the multiple stimulation patterns includes tonic stimulation.
8. The IPG of claim 1 wherein the IPG is programmable to apply a respective noise stimulation pattern to multiple electrodes.
9. The IPG of claim 8 wherein the IPG applies pulses by sequentially cycling through the multiple electrodes.
10. The IPG of claim 8 wherein the IPG applies pulses by randomly transitioning between the multiple electrodes.