System and method for delivering sub-threshold and super-threshold therapy to a patient
View Patent ↗A neuromodulation system includes modulation output circuitry and control circuitry. The modulation output circuitry may be configured to deliver therapeutic electrical energy including therapeutic sub-threshold electrical energy and therapeutic a super-threshold electrical energy. The sub-threshold electrical energy is below a patient-perception threshold and the super-threshold electrical energy is above the patient-perception threshold. The patient-perception threshold is a boundary below which a patient does not sense delivery of the electrical energy and above which the patient does sense delivery of the electrical energy. The control circuitry is configured to control the modulation output circuitry to deliver the therapeutic electrical energy using alternating cycles of the sub-threshold electrical energy below the patient-perception threshold and the super-threshold electrical energy above the patient-perception-threshold.
1. A method implemented using a neuromodulation system that includes a user interface and modulation output circuitry, the method comprising:
receiving one or more user inputs via the user interface that are used to at least partially control delivery of therapeutic electrical energy to targeted tissue to treat pain, wherein the therapeutic electrical energy includes therapeutic sub-threshold electrical energy having a pulse rate greater than 1500 Hz and therapeutic super-threshold electrical energy having a pulse rate less than 1500 Hz; and
controlling the modulation output circuitry to treat the pain based at least in part on the one or more user inputs, by delivering the therapeutic sub-threshold electrical energy during first times and the therapeutic super-threshold electrical energy during second times, wherein each of the therapeutic sub-threshold electrical energy and the therapeutic super-threshold electrical energy is independently effective with respect to each other to treat the pain.
2. The method of claim 1 , wherein the system includes a spinal cord modulation (SCM) system comprising a plurality of electrical terminals configured to be respectively coupled to a plurality of electrodes, wherein the modulation output circuitry is operably connected to the plurality of electrical terminals to deliver therapeutic electrical energy for alleviating pain to groups of electrodes, and wherein the modulation output circuitry includes independently-controlled current sources or independently controlled voltage sources, the method including:
controlling the modulation output circuitry to control a percentage of electrical energy assigned to each electrode, to use a group of electrodes to deliver the sub-threshold electrical energy during the first times, and to use another group of electrodes to deliver the super-threshold electrical energy during the second times.
3. The method of claim 2 , wherein the SCM system includes a memory with a time schedule programmed in the memory, the method including:
using the time schedule to automatically deliver the sub-threshold electrical energy during the first times and deliver the super-threshold electrical energy during the second times.
4. The method of claim 1 , wherein the receiving user input includes receiving user input to modify a modulation program configured to be implemented to deliver at least one of the therapeutic sub-threshold electrical energy during first times or the therapeutic super-threshold electrical energy during second times.
5. The method of claim 1 , wherein the receiving user input includes receiving user input to define a time schedule for delivering at least one of the therapeutic sub-threshold electrical energy during first times and the therapeutic super-threshold electrical energy during second times.
6. The method of claim 1 , wherein the receiving user input includes receiving user input to define the first times for delivering the therapeutic sub-threshold electrical energy.
7. The method of claim 1 , wherein the receiving user input includes receiving user input to define the second times for delivering the therapeutic super-threshold electrical energy.
8. The method of claim 1 , wherein the receiving user input includes receiving user input to define at least one absolute time for at least one of the first times or the second times.
9. The method of claim 1 , wherein the receiving user input includes receiving user input to define at least one relative time for at least one of the first times or the second times.
10. The method of claim 1 , wherein the first times do not overlap with the second times.
11. The method of claim 1 , wherein the first times overlap with the second times.
12. The method of claim 1 , wherein the pulse rate of the therapeutic sub-threshold electrical energy is greater than 2500 Hz, and the pulse rate of the therapeutic super-threshold electrical energy is less than 500 Hz.
13. The method of claim 1 , wherein the one or more user inputs are used to determine at least one modulation parameter of the therapeutic electrical energy.
14. The method of claim 1 , wherein the one or more user inputs are used to determine at least one of the first times during which the therapeutic sub-threshold electrical energy is delivered and the second times during which the therapeutic super-threshold electrical energy is delivered.
15. A non-transitory machine-readable medium including instructions, which when executed by a machine within a neuromodulation system that includes a user interface and modulation output circuitry, cause the machine to:
receive one or more user inputs via the user interface to define or modify delivery of therapeutic electrical energy to targeted tissue to treat pain, wherein the therapeutic electrical energy includes therapeutic sub-threshold electrical energy having a pulse rate greater than 1500 Hz, and therapeutic super-threshold electrical energy having a pulse rate less than 1500 Hz; and
control the modulation output circuitry to treat the pain, based at least in part on the one or more user inputs, by delivering the therapeutic sub-threshold electrical energy during first times and the therapeutic super-threshold electrical energy during second times, wherein each of the therapeutic sub-threshold electrical energy and the therapeutic super-threshold electrical energy is independently effective with respect to each other to treat the pain.
16. The non-transitory machine-readable medium of claim 15 , wherein the system includes a spinal cord modulation (SCM) system comprising a plurality of electrical terminals configured to be respectively coupled to a plurality of electrodes and the modulation output circuitry is operably connected to the plurality of electrical terminals to deliver therapeutic electrical energy for alleviating pain to specified groups of electrodes, wherein the modulation output circuitry includes independently-controlled current sources or independently controlled voltage sources, and wherein the instructions, which when executed by the machine, cause the machine to control the modulation output circuitry to control a percentage of electrical energy assigned to each electrode, to use a group of electrodes to deliver the sub-threshold electrical energy during the first times, and to use another group of electrodes to deliver the super-threshold electrical energy during the second times.
17. The non-transitory machine-readable medium of claim 15 , wherein the one or more user inputs are used to determine at least one modulation parameter of the therapeutic electrical energy.
18. The non-transitory machine-readable medium of claim 15 , wherein the one or more user inputs are used to determine at least one of the first times during which the therapeutic sub-threshold electrical energy is delivered and the second times during which the therapeutic super-threshold electrical energy is delivered.