Implantable optrode with a controller configured for operation in a stimulation mode and in a diagnostic mode
An optrode arrangement for delivering optical stimulation to target tissue in a patient, the optrode arrangement comprising an implantable optrode comprising at least one electrically powered light emitter and an electrical circuit and control lines for controlling the light emitter, whereby an associated controller has two modes of operation: a stimulation mode in which it is configured to control the light emitter to deliver optical stimulation to the target tissue and a diagnostic mode in which it is configured to determine a condition of the light emitter and/or the optrode.
1. An optrode arrangement for delivering optical stimulation to target tissue in a patient, the optrode arrangement comprising:
an implantable optrode comprising at least one electrically powered light emitter;
an electrical circuit and control lines for controlling the light emitter; and
a controller having two modes of operation, a stimulation mode in which the controller controls the light emitter to deliver optical stimulation to the target tissue and a diagnostic mode in which the controller determines a condition of one or both of the light emitter and/or the optrode;
wherein the optrode arrangement is configured such that a voltage above a threshold voltage must be applied to an input of the light emitter to cause it to emit light for optical stimulation and wherein during operation of the controller in the diagnostic mode a non-zero voltage applied to the input of the light emitter does not exceed said threshold voltage.
2. An optrode arrangement according to claim 1 , wherein the controller is configured to determine the condition of the light emitter to be normal or abnormal.
3. An optrode arrangement according to claim 2 , wherein the controller is configured to generate an alert in the case that it is determined that the condition of the light emitter is abnormal.
4. An optrode arrangement according to claim 2 , wherein the controller is configured, when it is determined that the condition of the light emitter is abnormal, to prevent subsequent operation in the stimulation mode.
5. An optrode arrangement according to claim 1 , wherein in the diagnostic mode of operation, the controller determines a condition of the light emitter based on at least a voltage drop across the light emitter.
6. An optrode arrangement according to claim 5 , wherein the controller comprises a diagnostic circuit configured to output a measure of voltage drop across the light emitter.
7. An optrode arrangement according to claim 6 , wherein the controller is configured to compare the output of said diagnostic circuit with an expected output for a normal condition of the light emitter and to determine that the light emitter has an abnormal condition when the output of the diagnostic circuit is different from the expected output.
8. An optrode arrangement according to claim 1 , comprising a thermal sensor for measuring a temperature of the optrode, wherein in the diagnostic mode of operation, the controller determines a condition of the light emitter based on at least an output from the thermal sensor.
9. An optrode arrangement according to claim 1 , wherein the optrode comprises a plurality of stimulation sites space apart along the optrode from one another, each stimulation site comprising at least one light emitter.
10. An optrode arrangement according to claim 9 , wherein each stimulation site comprises at least two light emitters.
11. An optrode arrangement according to claim 1 , wherein the or each light emitter is a light emitting diode.
12. An optrode arrangement according to claim 1 , wherein the target tissue is nerve cells.
13. An optrode arrangement for delivering optical stimulation to target tissue in a patient, the optrode arrangement comprising:
an implantable optrode comprising at least one electrically powered light emitter;
an electrical circuit and control lines for controlling the light emitter; and
a controller having two modes of operation, a stimulation mode in which the controller controls the light emitter to deliver optical stimulation to the target tissue and a diagnostic mode in which the controller determines a condition of one or both of the light emitter and/or the optrode;
wherein the optrode arrangement is configured such that a voltage above a threshold voltage must be applied to an input of the light emitter to cause it to emit light for optical stimulation and wherein during operation of the controller in the diagnostic mode a non-zero voltage applied to the input of the light emitter does not exceed said threshold voltage,
wherein in the diagnostic mode of operation, the controller determines a condition of the light emitter based on at least a voltage drop across the light emitter.
14. An optrode arrangement according to claim 11 , wherein the controller comprises a diagnostic circuit configured to output a measure of voltage drop across the light emitter.
15. An optrode arrangement according to claim 11 , wherein the controller is configured to compare the output of said diagnostic circuit with an expected output for a normal condition of the light emitter and to determine that the light emitter has an abnormal condition when the output of the diagnostic circuit is different from the expected output.
16. An optrode arrangement according to claim 11 , wherein the controller is configured to determine the condition of the light emitter to be normal or abnormal.
17. An optrode arrangement according to claim 16 , wherein the controller is configured to generate an alert in the case that it is determined that the condition of the light emitter is abnormal.
18. An optrode arrangement according to claim 16 , wherein the controller is configured, when it is determined that the condition of the light emitter is abnormal, to prevent subsequent operation in the stimulation mode.
19. An optrode arrangement according to claim 11 , wherein the optrode comprises a plurality of stimulation sites space apart along the optrode from one another, each stimulation site comprising at least one light emitter.
20. An optrode arrangement for delivering optical stimulation to target tissue in a patient, the optrode arrangement comprising:
an implantable optrode comprising at least one electrically powered light emitter;
an electrical circuit and control lines for controlling the light emitter; and
a controller having two modes of operation, a stimulation mode in which the controller controls the light emitter to deliver optical stimulation to the target tissue and a diagnostic mode in which the controller determines a condition of one or both of the light emitter and/or the optrode;
wherein the optrode arrangement is configured such that a voltage above a threshold voltage must be applied to an input of the light emitter to cause it to emit light for optical stimulation and wherein during operation of the controller in the diagnostic mode a non-zero voltage applied to the input of the light emitter does not exceed said threshold voltage, and
a thermal sensor for measuring a temperature of the optrode, wherein in the diagnostic mode of operation, the controller determines a condition of the light emitter based on at least an output from the thermal sensor.