Fluid processing based on inflatable bags, mixing system, and method of use thereof
A device and a method for mixing a fluid in a specimen bag is provided herein. In one embodiment, the device includes a mechanism for creating a first vortex and a second vortex. The first vortex is on a first side of a bag containing the fluid, and the second vortex is on a second side of the bag. The mechanism includes a first inflatable airbag and a second inflatable airbag. The first inflatable airbag is configured to create the first vortex when inflated and the second inflatable airbag is deflated. The second inflatable airbag is configured to create the second vortex when inflated and the first inflatable airbag is deflated.
1. A device for mixing biological specimens in a single compartment specimen bag, the device comprising:
a single compartment specimen bag,
a support structure comprising a base plate configured to support the single compartment specimen bag,
a cover that fits over the support structure, wherein the cover is configured to pivot between an open position and a closed position,
at least one squeezing lip protruding from one of the support structure and the cover,
at least one inflatable airbag installed under the cover, and configured to directly contact the single compartment specimen bag when the cover is in the closed position and the at least one inflatable airbag is inflated by a pneumatic system, and
a lock to lock the cover in the closed position during mixing of biological specimens in the single compartment specimen bag,
wherein the single compartment specimen bag is delimited by the squeezing lip forming a first sub-compartment, a second sub-compartment, and a narrower path linking the first and second sub-compartments than without the squeezing lip, and the at least one inflatable airbag comprises a first inflatable airbag configured to provide alternate progressive push and pull movement transmitted to the first sub-compartment of the single compartment specimen bag by progressively inflating and deflating the first inflatable airbag with the pneumatic system and a second inflatable airbag configured to work in tandem with the first inflatable bag to provide alternate progressive pull and push movement transmitted to the second sub-compartment of the single compartment specimen bag by progressively inflating and deflating the second inflatable airbag with the pneumatic system.
2. The device of claim 1 , further comprising a temperature control means for maintaining the biological specimens at a controlled temperature.
3. The device of claim 1 , further comprising an entry tube in fluid communication with the single compartment specimen bag for adding additive to the specimen bag.
4. The device of claim 1 , wherein the at least one inflatable airbag is a pneumatic bag.
5. The device of claim 1 , wherein the first and second inflatable airbags are pneumatic bags.
6. The device of claim 1 , further comprising a CPU configured to control the pneumatic system.
7. The device of claim 1 , wherein the first sub-compartment is smaller than the second sub-compartment, the second sub-compartment further comprising an entry tube in fluid communication with the single compartment specimen bag for adding additive to the specimen bag.
8. The device of claim 1 , wherein the at least one squeezing lip is removably fixed on one of the cover and the support structure.
9. A device for mixing biological specimens, the device comprising:
a dual compartment specimen bag, the dual compartment specimen bag having a first and a second sub-compartment, wherein the first and the second sub-compartments are separated by an integrated division defining a narrowed path linking the first and second sub-compartments,
a support structure comprising a base plate configured to support the dual compartment specimen bag,
a cover that fits over the support structure, and is pivotally mounted on the support structure wherein the cover can move between an open position and a closed position,
at least one inflatable airbag installed under the cover configured to directly contact the dual compartment specimen bag when the cover is in the closed position and the at least one inflatable airbag is inflated by a pneumatic system, wherein the at least one inflatable bag when inflated contacts the first sub-compartment of the dual compartment specimen bag to squeeze the first sub-compartment of the dual compartment specimen bag and displace the contained specimen into the second sub-compartment of the dual compartment specimen bag, and
a lock to lock the cover in the closed position to prevent the cover from opening as a result of inflation of the at least one airbag during mixing.
10. The device of claim 9 , further comprising a temperature control means for maintaining the biological specimens at a controlled temperature.
11. The device of claim 9 , further comprising an entry tube in fluid communication with the dual compartment specimen bag for adding additive to the specimen bag.
12. The device of claim 9 , wherein the at least one inflatable airbag is a pneumatic bag.
13. The device of claim 9 , wherein the at least one inflatable airbag comprises a first inflatable airbag configured to provide alternate progressive push and pull movement transmitted to the first sub-compartment of the dual compartment specimen bag by progressively inflating and deflating the first inflatable airbag and a second inflatable airbag configured to work in tandem with the first inflatable bag to provide alternate progressive pull and push movement transmitted to the second sub-compartment of the dual compartment specimen bag by progressively inflating and deflating the second inflatable airbag.
14. The device of claim 9 , further comprising a CPU configured to control the pneumatic system.
15. The device of claim 9 , wherein the first sub-compartment is smaller than the second sub-compartment, the second sub-compartment further comprising an entry tube in fluid communication with the dual compartment specimen bag for adding additive to the specimen bag.