Composition and method for improving the appearance of skin
Low pH cosmetic compositions and methods for improving the appearance of skin. The low pH cosmetic compositions herein include a saccharide and, optionally, one or more additional skin care actives to improve the appearance of skin. The lower pH reduces or even eliminates some of the skin health and appearance drawbacks associated with saccharide induced glycation.
1. A topical skin care composition, comprising:
(a) about 0.01% to about 15%, by weight, of a saccharide; and
(b) a dermatologically acceptable carrier, wherein the composition has a pH of equal to or less than 3.5 and the composition does not increase glycation over time in the Advanced Glycation End Product Assay.
2. The composition of claim 1 , wherein the saccharide is selected from the group consisting of glyceraldehyde, dihydroxyacetone, erythrose, threose, erythrulose, ribose, arabinose, ribulose, xylulose, xylose, lyxose, deoxyribose, dibulose, ribonic acid, ribaric acid, allose, altrose, glucose, galactose, mannose, fructose, idose, talose, psicose, trehalose, sorbose, tagatose, gulose, fucose, rhamnose, glucuronic acid, glucaric acid, gularic acid, galactaric acid, galacturonic acid, sedoheptulose, neuraminic acid, ribulose 5-phosphate, xylulose 5-phosphate, ribose 5-phosphate, sedoheptulose 7-phosphate, glyceraldehyde 3-phosphate, fructose 6-phosphate, erythrose 4-phosphate, glucose 6-phosphate, 6-phosphoglucono-δ-lactone, 6-phosphogluconate, dihydroxyacetone phosphate, fructose 1,6-bisphosphate, N-acetylglucosamine, N-acetylgalactosamine, glucosamine, and combinations thereof.
3. The composition of claim 2 , wherein the saccharide is ribose or trehalose.
4. The composition of claim 1 , further comprising about 0.1% to about 10%, by weight, of a stable fatty alcohol thickener selected from the group consisting of a cetyl alcohol, a stearyl alcohol, and combinations thereof.
5. The composition of claim 4 , wherein the stable fatty alcohol thickener is present at about 1% to about 5%, by weight.
6. The composition of claim 1 , further comprising an additional skin care active selected from the group consisting of sunscreens, oil control agents, anti-inflammatory agents, moisturizing agents, exfoliating agents, skin lightening agents, anti-acne agents, anti-wrinkle agents, antimicrobials, antifungals, and combinations of distinct agents thereof.
7. The composition of claim 6 , wherein the additional skin care active comprises about 0.01% to about 15%, by weight, niacinamide.
8. The composition of claim 6 , wherein the addition skin care active is a sunscreen selected from the group consisting of 2-ethylhexyl-p-methoxycinnamate, 4,4′-t-butyl methoxydibenzoyl-methane, 2-hydroxy-4-methoxybenzophenone, octyldimethyl-p-aminobenzoic acid, digalloyltrioleate, 2,2-dihydroxy-4-methoxybenzophenone, ethyl-4-(bis(hydroxypropyl))aminobenzoate, 2-ethylhexyl-2-cyano-3,3-diphenylacrylate, 2-ethylhexyl-salicylate, glyceryl-p-aminobenzoate, trimethylcyclohexylsalicylate, menthyl anthranilate, p-dimethyl-aminobenzoic acid or aminobenzoate, 2-ethylhexyl-p-dimethyl-amino-benzoate, 2-phenylbenzimidazole-5-sulfonic acid, 2-(p-dimethylaminophenyl)-5-sulfonicbenzoxazoic acid, octocrylene, zinc oxide, benzylidene camphor, titanium dioxide, and combinations thereof.
9. The composition of claim 6 , wherein the additional skin active is selected from the group consisting of sucrose dilaurate, N-acyl phenyalanine, hexamidine, hexyldecanol, N-acetyl glucosamine, a combination of 1,2 hexandiol and 1,2 octandiol, hyaluronic acid, sodium hyaluronate, lactic acid, lactate salts, hydroxycinnamic acid, hexylresorcinol, glycyrrhizic acid, bisabolol, and combinations thereof.
10. The composition of claim 1 , wherein the composition does not increase a yellowness (b*) value over time in the AGE assay.
11. The composition of claim 1 , wherein the composition does not increase a fluorescence intensity value over time in the AGE Assay.
12. The composition of claim 1 , further comprising an emulsifier.
13. A topical skin care composition, comprising:
(a) about 0.01% to about 15%, by weight, of trehalose;
(b) glycerin;
(c) a third agent as thickener; and
(d) a fourth agent as dermatologically acceptable carrier, wherein the composition has a pH of equal to or less than 3.5 and the composition does not increase in the Advanced Glycation End Product Assay.
14. The skin care composition of claim 13 , wherein the dermatologically acceptable carrier is in the form of an oil-in-water emulsion.
15. The skin care composition of claim 14 , wherein an oil phase of the oil-in-water emulsion comprises a silicone oil.
16. The skin care composition of claim 13 , wherein the composition exhibits a change in fluorescence intensity (ΔFLR) of less than 0 relative to an initial FLR at time 0 in the Advanced Glycation End Product Assay after 38 days.