Device for chemically assisted dissection
A device and a method for delivering a solution to tissues and/or organs. The solution contains at least one solvent and at least one solute. The device includes at least one chamber which contains sodium 2-mercaptoethanesulfonate in powder form. The method includes the steps of dissolving the solute in the solvent inside the device. The resulting solution is delivered immediately to tissues and/or organs to facilitate dissection.
1. A device for delivering a solution for use in surgery comprising a first chamber housing sterile sodium 2-mercaptoethanesulfonate in solid form, a second chamber for housing a solvent and at least one outlet for delivering the solution, wherein said outlet is in fluid communication with at least one of the chambers; and wherein said chambers are separated from each other by at least one disruptable membrane and are in fluid communication with each other upon disruption of said membrane thereby forming the solution suitable for surgery, wherein the solution is devoid of an antioxidant and/or stabilizing agent.
2. The device according to claim 1 , wherein the first chamber and/or the second chamber are movable.
3. The device according to claim 1 , further comprising at least one air vent for air evacuation of the device and/or air insertion into the device.
4. The device according to claim 1 , wherein the at least one outlet is suitable for connection to a surgical device or to a delivery tube via a pump system.
5. The device according to claim 1 , wherein the solvent is saline water.
6. The device according to claim 1 , wherein the sodium 2-mercaptoethanesulfonate in solid form is sterilized by gamma irradiation at a dose of 20 to 50 kGy.
7. The device according to claim 1 , wherein the solution is fed through a microfilter having a pore size of 0.1 to 3 μm.
8. A kit comprising a solvent for dissolving sodium 2-mercaptoethanesulfonate and a device according to claim 1 .
9. The kit according to claim 8 , wherein the solvent is saline water.
10. A method for weakening inter-tissues and/or organs adhesion to facilitate dissection by delivering a sterile solution to tissues and/or organs, wherein the solution is devoid of an antioxidant and/or stabilizing agent, comprising:
dissolving a sterile solute containing a powder consisting of sodium 2-mercaptoethanesulfonate in a solvent inside a device thereby obtaining the solution; and
delivering the obtained solution to said tissues and/or organs,
wherein delivery of the solution is performed at most 24 hours after obtaining the solution.
11. The method according to claim 10 , wherein the concentration of sodium 2-mercaptoethanesulfonate in the solution is from 5% to 50%.
12. The method according to claim 10 , wherein the solvent is saline.