IP Library › Granted Patent US 11,116,759
Granted Patent B2
US 11,116,759 · App. 16/142,691 · Granted Sep 14, 2021

Method of treating cancer

Inventors: Dana T. Aftab (San Rafael, CA); Frauke Schimmoller (Menlo Park, CA)
Assignee: Exelixis, Inc.
A61K31/47A61P35/04
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Quick Facts
Patent No.
US 11,116,759
App. No.
16/142,691
Granted
Sep 14, 2021
Kind
B2
Abstract

This invention is directed to the treatment of cancer, particularly ocular melanoma, with a dual inhibitor of MET and VEGF such as Compound 1.

Claims (5)

1. A method for treating metastatic ocular melanoma, comprising administering to a patient in need of such treatment a therapeutically effective amount of Compound 1:

or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , wherein the ocular melanoma is choroidal or iris melanoma.

3. The method of claim 1 , wherein Compound 1 is the (L)- or (D)-malate salt.

4. The method of claim 3 , wherein Compound 1 or a pharmaceutically acceptable salt thereof, is administered as a pharmaceutical composition comprising a pharmaceutically acceptable carrier, excipient, or diluent.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 16, 2020
From: AFTAB, DANA T.; SCHIMMOLLER, FRAUKE
To: EXELIXIS, INC.
Reel/Frame 054081/0032 →
Continuity (5)
Continuation 14933801 · Nov 5, 2015
Continuation 14668312 · Mar 25, 2015
Continuation 13438964 · Apr 4, 2012
Provisional Application 61471367 · Apr 4, 2011
Related Publication 20190091215A1 · Mar 28, 2019