IP Library Granted Patent US 11,116,967
Granted Patent B2
US 11,116,967 · App. 15/986,049 · Granted Sep 14, 2021

Electrode system, device and method for the treatment of eye diseases, in particular dry eye

Inventors: Alessandro De Toni (Padua, IT); Alessandro Pozzato (Vicenza, IT); Gianantonio Pozzato (Vicenza, IT); Alfredo Ruggeri (Padua, IT); Matteo Scaramuzza (Chirignago, IT); Antonio Trani (Dueville, IT)
Assignee: RESONO OPHTHALMIC S.R.L.
A61N1/06A61N1/0484A61N1/36046
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Quick Facts
Patent No.
US 11,116,967
App. No.
15/986,049
Granted
Sep 14, 2021
Kind
B2
Abstract

A method for treating an eye, including the step of applying an electromagnetic wave of distorted sinusoidal current with a resonance frequency and having related harmonics on an eye, an eye orbit, a temple, eyelid areas or a part thereof.

Claims (10)

1. A method for treating dry eye and ophthalmic diseases of the cornea and the retina, comprising the step of at least temporarily remitting dry eye and enhancing tear production by uniformly transmitting an electromagnetic wave of distorted sinusoidal current with a resonance frequency and comprising related harmonics on an eye, an eye orbit, a temple, eyelid areas or a part thereof, wherein the resonance frequency is 4 MHz.

2. The method according to claim 1 , wherein the harmonics include the second harmonic and the third harmonic.

3. The method according to claim 1 , wherein the harmonics are up to 64 MHz.

4. The method according to claim 1 , wherein the ophthalmic diseases are blepharitis or epithelial wounds.

5. The method according to claim 1 , wherein the ophthalmic diseases are retinitis, pigmentosa or age-related degenerative maculopathy.

6. The method according to claim 1 , wherein said application is carried out by an electrode system comprising one or more electrodes wherein (a) a portion of said one or more electrodes intended to be applied in contact with the eye, the eye orbit, the temple, the eyelid areas or a part of them, respectively imitates the surface shape of the eye, the eye orbit, the temple, the eyelid areas or a part of them or wherein (b) a portion of said one or more electrodes intended to be applied in contact with the eye the eye orbit, the temple, the eyelid areas or a part of them is flexible and adaptable in its shape in such a way that in the cases (a) and (b) a form-fit coupling is achievable between said portion of said one or more electrodes and the surface shape of the eye, the eye orbit, the temple, the eyelid areas or a part of them, wherein said portion of said one or more electrodes intended to be applied in contact with the eye, the eye orbit, the temple, the eyelid areas or a part of them is fed or feedable with an electromagnetic wave of distorted sinusoidal current with a 4 MHz resonance frequency, which includes the related harmonics.

7. The method according to claim 1 , wherein said application is carried out by an electrostimulation device comprising:

an electrode system comprising one or more electrodes wherein (a) a portion of said one or more electrodes intended to be applied in contact with the eye, the eye orbit, the temple, the eyelid areas or a part of them, respectively imitates the surface shape of the eye, the eye orbit, the temple, the eyelid areas or a part of them or wherein (b) a portion of said one or more electrodes intended to be applied in contact with the eye, the eye orbit, the temple, the eyelid areas or a part of them is flexible and adaptable in its shape in such a way that in the cases (a) and (b) a form-fit coupling is achievable between said portion of said one or more electrodes and the surface shape of the eye, the eye orbit, the temple, the eyelid areas or a part of them, wherein said portion of said one or more electrodes intended to be applied in contact with the eye, the eye orbit, the temple, the eyelid areas or a part of them is fed or feedable with an electromagnetic wave of distorted sinusoidal current with a 4 MHz resonance frequency, which includes the related harmonics; and

a radiofrequency circuit suitable to emit an electromagnetic wave of distorted sinusoidal current with a 4 MHz resonance frequency, which includes the related harmonics, in which the electromagnetic wave of distorted sinusoidal current feeds said one or more electrodes, and in particular said portion of said one or more electrodes intended to be applied in contact with the eye, the eye orbit, the temple, the eyelid areas or a part of them.

8. The method according to claim 1 , including transmitting the electromagnetic wave to most of the meibomian glands and most of the lacrimal glands.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 22, 2018
From: RUPP, MARKUS
To: PERI GMBH
Reel/Frame 046660/0203 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 22, 2018
From: DE TONI, ALESSANDRO; POZZATO, ALESSANDRO; POZZATO, GIANANTONIO; RUGGERI, ALFREDO; SCARAMUZZA, MATTEO; TRANI, ANTONIO
To: RESONO OPHTHALMIC S.R.L.
Reel/Frame 045871/0768 →
Priority Claims (1)
IT 102015000066819 · Oct 29, 2015 · national
Continuity (2)
Division 15540721
Related Publication 20180339151A1 · Nov 29, 2018