IP Library › Granted Patent US 11,117,957
Granted Patent B2
US 11,117,957 · App. 16/141,911 · Granted Sep 14, 2021

Anti-BAG3 antibodies for therapeutic use

Inventor: Maria Caterina Turco (Avellino, IT)
Assignee: BIOUNIVERSA S.R.L.
C07K16/18C07K16/303A61K2039/505A61K2039/54C07K2317/14C07K2317/73C07K2317/76
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,117,957
App. No.
16/141,911
Granted
Sep 14, 2021
Kind
B2
Abstract

The present invention relates to the use of BAG3 antibodies as a medicament, in particular for use in the treatment of pancreatic tumours or other pathologies of an immune, inflammatory, neoplastic and/or degenerative nature.

Claims (6)

1. A method for treating pancreatic tumor, comprising:

administering to a subject in need thereof an anti-BAG3 antibody produced by clone AC-1, and

inhibiting the activity of extra-cellular BAG3 proteins on activation of macrophages,

wherein said anti-BAG3 antibody binds to a BAG3 protein having the amino acid sequence of SEQ ID NO: 5.

2. The method according to claim 1 , wherein said anti-BAG3 antibody recognizes one of the amino acid sequences of SEQ ID NOs: 1-4.

3. The method according to claim 1 , wherein said anti-BAG3 antibody is produced by using an immunogen comprising four peptides having the amino acid sequences of SEQ ID NOs: 1-4.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 19, 2022
From: BIOUNIVERSA S.R.L.
To: FIBROSYS S.R.L.
Reel/Frame 061141/0962 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 5, 2021
From: TURCO, MARIA CATERINA
To: BIOUNIVERSA S.R.L.
Reel/Frame 057097/0048 →
Priority Claims (1)
IT MI2013A000403 · Mar 18, 2012 · national
Continuity (2)
Continuation 14651213
Related Publication 20190010221A1 · Jan 10, 2019