IP Library › Granted Patent US 11,142,731
Granted Patent B2
US 11,142,731 · App. 15/854,355 · Granted Oct 12, 2021

Plate

Inventors: Tomoko Kunitomi (Taito-ku, JP); Yoichi Makino (Taito-ku, JP)
Assignee: TOPPAN PRINTING CO., LTD.
C12M1/34B01L3/50851C12M1/00C12Q1/6825G01N21/64G01N21/6452B01L3/563B01L7/52B01L2200/026B01L2300/069B01L2300/0654B01L2300/0819
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Quick Facts
Patent No.
US 11,142,731
App. No.
15/854,355
Granted
Oct 12, 2021
Kind
B2
Abstract

An analytical device includes a plate including a first substrate having a front surface and a back surface and a second substrate facing the back surface of the first substrate such that at least one detection space observable from outside is formed between the second substrate and the back surface of the first substrate, and an adapter. The first substrate has a first port having a through hole formed through the front surface and communicated with the detection space for delivering a liquid-containing substance into the detection space, the first substrate has a second port having a through hole formed through the front surface and communicated with the detection space for discharging a liquid-containing substance or a gas from the detection space, and the adapter is attachable to and detachable from the first port and the second port, and the front surface of the first substrate without the adapter is flat.

Claims (24)

1. An analytical device, comprising:

a plate comprising a first substrate, a second substrate facing the first substrate, and a side wall extending between the first and second substrates such that at least one detection space is formed between the second substrate and the first substrate and that the first substrate has a plurality of ports communicated with the detection space; and

an adapter having a first end and a second end on an opposite end with respect to the first end such that at least one of the first and second ends is configured to be fitted into at least one of the plurality of ports in the first substrate and has an abutment portion configured to abut against a surface of the second substrate inside the detection space and a cutout portion configured to form a flow path to the detection space inside the detection space when fitted into the one of the plurality of ports,

wherein at least one of the first and second substrates comprises a transparent material such that the detection space is observable from outside the plate, the plurality of ports includes a first port configured to deliver a liquid-containing substance into the detection space, and a second port configured to discharge the liquid-containing substance or a gas from the detection space.

2. The analytical device of claim 1 , wherein the adapter comprises a tube having the first end configured to be fitted into the one of the plurality of ports, and the second end configured to be an open end with a larger diameter than the first end.

3. The analytical device of claim 1 , wherein the plate is formed such that the at least one detection space comprises a plurality of detection spaces, the adapter has the first end configured to be fitted into the one of the plurality of ports communicated with the one of the detection spaces, and the second end configured to be fitted into the one of the plurality of ports communicated with another one of the detection spaces.

4. The analytical device of claim 1 , wherein the adapter has an inner wall to which a reagent is fixed, and is configured to deliver the reagent into the detection space through the cutout portion.

5. The analytical device of claim 2 , wherein the adapter has an inner wall to which a reagent is fixed, and is configured to deliver the reagent into the detection space through the cutout portion.

6. The analytical device of claim 3 , wherein the adapter has an inner wall to which a reagent is fixed, and is configured to deliver the reagent into the detection space through the cutout portion.

7. The analytical device of claim 1 , wherein the adapter has the first end configured to be fitted to the one of the plurality of ports, and the second end configured to be an open end or a closed end with a larger diameter than the first end.

8. The analytical device of claim 7 , wherein the adapter includes an absorbing material and is configured to absorb an effluent discharged from the detection space through the cutout portion.

9. The analytical device of claim 1 , wherein at least one of the first substrate and the second substrate has transparency that allows detection of fluorescence or luminescence in the detection space from outside the plate.

10. The analytical device of claim 1 , wherein both the first substrate and the second substrate have transparency that allows detection of fluorescence or luminescence in the detection space from outside the plate.

11. The analytical device of claim 1 , wherein the plate is formed such that the at least one detection space comprises a plurality of detection spaces, and the adapter has the first end configured to be fitted into the one of the plurality of ports communicated with the one of the detection spaces, and the second end configured to be fitted into the one of the plurality of ports communicated with another one of the detection spaces such that the adapter is configured to establish communication between the plurality of the detection spaces.

12. The analytical device of claim 1 , wherein at least one of the first substrate and the second substrate has a surface having at least one pore positioned in the detection space, and the at least one pore has a capacity of 1 pl or less.

13. The analytical device of claim 1 , further comprising:

a film or lid configured to cover one of the plurality of ports such that the film or lid is detachable or cut through.

14. The analytical device of claim 1 , wherein the plate is configured to be heated such that the detection space is heated.

15. The analytical device of claim 1 , wherein the side wall comprises an adhesive layer.

16. The analytical device of claim 1 , wherein the plate is formed such that the at least one detection space comprises a plurality of detection spaces formed between the first and second substrates.

17. The analytical device of claim 1 , wherein the at least one of the first and second ends is configured to fit into the at least one of the plurality of ports in the first substrate such that liquid does not leak when fitted into the at least one of the plurality of ports in the first substrate.

18. The analytical device of claim 1 , wherein the adapter comprises an elastic material, and the at least one of the first and second ends is configured to fit into the at least one of the plurality of ports in the first substrate such that liquid does not leak when fitted into the at least one of the plurality of ports in the first substrate.

19. The analytical device of claim 1 , wherein the plate has flat surfaces on exterior sides of the plate.

20. The analytical device of claim 1 , wherein the at least one of the first and second ends has the cutout portion having a cross-sectional area equal to a cross-sectional area of a flow path of the detection space when fitted into the at least one of the plurality of ports in the first substrate.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 26, 2017
From: KUNITOMI, TOMOKO; MAKINO, YOICHI
To: TOPPAN PRINTING CO., LTD.
Reel/Frame 044486/0291 →
Priority Claims (1)
JP JP2015-129012 · Jun 26, 2015 · national
Continuity (2)
Continuation PCTJP2016068803 · Jun 24, 2016
Related Publication 20180119078A1 · May 3, 2018