Dose delivery device with cover connected to dose chamber seal
Dose delivery device with partially or fully surrounding cover may be removed to open fluid communication with a dose chamber. The cover may allow an inhaler to be stored in sterile or otherwise in a controlled environment prior to use, and removal of the cover may automatically prepare the inhaler for use.
1. A dose delivery device, comprising:
a body including a mouthpiece having an outlet, the body defining a flow path extending from an inlet to the outlet;
a dose chamber containing a dose to be delivered to a subject via the mouthpiece;
a seal that closes fluid communication between the flow path and the dose chamber; and
a cover that completely surrounds the body and the dose chamber, the cover including at least one barrier layer,
wherein the cover is connected to the seal such that separation of the cover from the body and the dose chamber causes the seal to open fluid communication between the flow path and the dose chamber, wherein the seal includes a wall that is slidably engaged with the body and configured to be guided in linear movement relative to the body across an opening of the dose chamber when moved from a closed position to an open position upon removal of the cover.
2. The device of claim 1 , wherein a portion of the at least one barrier layer near the mouthpiece outlet is attached to a tab that extends to the seal.
3. The device of claim 1 , wherein the body includes a handle arranged for gripping by a user to support the device during use.
4. The device of claim 3 , wherein the handle extends away from the mouthpiece in a direction along the flow path.
5. The device of claim 1 , wherein the cover includes a pair of barrier layers, a first layer of the pair of barrier layers forming a blister in which the body and the dose chamber are positionable, and a second layer of the pair of barrier layers sealed to the first layer to enclose the blister.
6. The device of claim 5 , wherein the dose chamber has a spoon shape and is arranged to engage the body at a handle portion of the spoon shape.
7. The device of claim 1 , wherein the dose chamber defines two separate spaces in which dose is located and is deliverable to the flow path.
8. The device of claim 1 , wherein the seal includes a portion that extends along an outer surface of the mouthpiece to a position near the dose chamber.
9. The device of claim 1 , wherein the body and the dose chamber define an inlet opening to the dose chamber and an outlet opening from the dose chamber to the flow path.
10. The device of claim 1 , wherein the dose chamber is arranged such that air flow into the dose chamber circulates in the dose chamber to entrain dose.
11. The device of claim 1 , wherein the dose chamber and the body are arranged such that dose-entrained air flowing from the dose chamber to the flow path enters the flow path in a direction perpendicular to flow in the flow path.
12. The device of claim 1 , wherein the dose chamber and the body are arranged such that dose-entrained air flowing from the dose chamber to the flow path enters the flow path at a restriction in the flow path.
13. The device of claim 1 , wherein flow in the flow path is along an axis from the inlet to the outlet.