IP Library › Granted Patent US 11,169,236
Granted Patent B2
US 11,169,236 · App. 16/571,316 · Granted Nov 9, 2021

Phase correction for echo-planar imaging

Inventors: Kun Zhou (Shenzhen, CN); Wei Liu (Shenzhen, CN); Yulin Chang (Watertown, MA); Uvo Hölscher (Erlangen, DE); William Scott Hoge (Watertown, MA); Jonathan Rizzo Polimeni (Cambridge, MA)
Assignee: The General Hospital Corporation
G01R33/5618G01R33/4818G01R33/56545G01R33/56554
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Quick Facts
Patent No.
US 11,169,236
App. No.
16/571,316
Granted
Nov 9, 2021
Kind
B2
Abstract

Systems and methods include conversion of a first frame of k-space data acquired using a first initial readout polarity to first hybrid (k x , y)-space data, conversion of a second frame of k-space data acquired using a second initial readout polarity to second hybrid (k x , y)-space data, determination of a relationship between phase difference and y-position based on phase differences between a plurality of pixels located at k x =a of first hybrid (k x , y)-space data and a plurality of pixels at k x =b of second hybrid (k x , y)-space data, where a and b are constants, modification of the second hybrid (k x , y)-space data based on the relationship, conversion of the modified second hybrid (k x , y)-space data to a modified second frame of k-space data, generation of two single-polarity readout k-space frames based on the first frame of k-space data and the modified second frame of k-space data, and correction of a third frame of EPI image data based on the two single-readout polarity k-space frames.

Claims (67)

1. A system comprising:

a chassis defining a bore;

a main magnet to generate a polarizing magnetic field within the bore;

a gradient system to apply a gradient magnetic field to the polarizing magnetic field;

a radio frequency system to transmit RF pulses to an object disposed within the bore and to receive signals from the object; and

a computing system to execute program code to:

acquire a first frame of k-space data using a first initial readout polarity;

acquire a second frame of k-space data using a second initial readout polarity opposite to the first initial readout polarity;

convert the first frame of k-space data to first hybrid (k x , y)-space data;

convert the second frame of k-space data to second hybrid (k x , y)-space data;

determine a relationship between phase difference and y-position based on phase differences between a plurality of pixels located at k x =a of first hybrid (k x , y)-space data and a plurality of pixels at k x =b of second hybrid (k x , y)-space data, where a and b are constants;

modify the second hybrid (k x , y)-space data based on the relationship;

convert the modified second hybrid (k x , y)-space data to a modified second frame of k-space data; and

generate two single-polarity readout k-space frames based on the first frame of k-space data and the modified second frame of k-space data.

2. A system according to claim 1 , wherein determination of the relationship comprises:

identification of a plurality of pairs of hybrid (k x , y)-space pixels, where each pair includes a pixel of the first hybrid (k x , y)-space data and a pixel of the second hybrid (k x , y)-space data located at a same y-position; and

determination of a phase difference between the pixels of each pair of the plurality of pairs.

3. A system according to claim 2 , wherein a=b=0.

4. A system according to claim 2 , wherein a does not equal b.

5. A system according to claim 1 , wherein modifying the second hybrid (k x , y)-space data based on the relationship comprises:

determining a phase correction associated with each pixel of the second hybrid (k x , y)-space data based on the relationship and the y-position of the pixel; and

for each pixel of the second hybrid (k x , y)-space data, applying the associated phase correction to the pixel to generate corrected second hybrid (k x , y)-space data.

6. A system according to claim 1 , the computing system to execute program code to:

correct a third frame of EPI image data based on the two single-readout polarity k-space frames.

7. A system according to claim 1 , the computing system to execute program code to:

phase-correct the first frame of k-space data and the second frame of k-space data in the k x -direction.

8. A method comprising:

acquiring a first frame of k-space data using a first initial readout polarity;

acquiring a second frame of k-space data using a second initial readout polarity opposite to the first initial readout polarity;

converting the first frame of k-space data to first hybrid (k x , y)-space data;

converting the second frame of k-space data to second hybrid (k x , y)-space data;

determining a relationship between phase difference and y-position based on phase differences between a plurality of pixels located at k x =a of first hybrid (k x , y)-space data and a plurality of pixels at k x =b of second hybrid (k x , y)-space data, where a and b are constants;

modifying the second hybrid (k x , y)-space data based on the relationship;

converting the modified second hybrid (k x , y)-space data to a modified second frame of k-space data; and

generating two single-polarity readout k-space frames based on the first frame of k-space data and the modified second frame of k-space data.

9. A method according to claim 8 , wherein determining the relationship comprises:

identifying a plurality of pairs of hybrid (k x , y)-space pixels, where each pair includes a pixel of the first hybrid (k x , y)-space data and a pixel of the second hybrid (k x , y)-space data located at a same y-position; and

determining a phase difference between the pixels of each pair of the plurality of pairs.

10. A method according to claim 9 , wherein a=b=0.

11. A method according to claim 9 , wherein a does not equal b.

12. A method according to claim 8 , wherein modifying the second hybrid (k x , y)-space data based on the relationship comprises:

determining a phase correction associated with each pixel of the second hybrid (k x , y)-space data based on the relationship and the y-position of the pixel; and

for each pixel of the second hybrid (k x , y)-space data, applying the associated phase correction to the pixel to generate corrected second hybrid (k x , y)-space data.

13. A method according to claim 8 , further comprising:

correcting a third frame of EPI image data based on the two single-readout polarity k-space frames.

14. A method according to claim 8 , further comprising:

phase-correcting the first frame of k-space data and the second frame of k-space data in the k x -direction.

15. A computing system comprising:

a memory storing processor-executable program code; and

one or more processors to execute the program code to:

convert a first frame of k-space data acquired using a first initial readout polarity to first hybrid (k x , y)-space data;

convert a second frame of k-space data acquired using a second initial readout polarity to second hybrid (k x , y)-space data;

determine a relationship between phase difference and y-position based on phase differences between a plurality of pixels located at k x =a of first hybrid (k x , y)-space data and a plurality of pixels at k x =b of second hybrid (k x , y)-space data, where a and b are constants;

modify the second hybrid (k x , y)-space data based on the relationship;

convert the modified second hybrid (k x , y)-space data to a modified second frame of k-space data;

generate two single-polarity readout k-space frames based on the first frame of k-space data and the modified second frame of k-space data; and

correct a third frame of EPI image data based on the two single-readout polarity k-space frames.

16. A computing system according to claim 15 , wherein determination of the relationship comprises:

identification of a plurality of pairs of hybrid (k x , y)-space pixels, where each pair includes a pixel of the first hybrid (k x , y)-space data and a pixel of the second hybrid (k x , y)-space data located at a same y-position; and

determination of a phase difference between the pixels of each pair of the plurality of pairs.

17. A computing system according to claim 16 , wherein a=b=0.

18. A computing system according to claim 16 , wherein a does not equal b.

19. A computing system according to claim 15 , wherein modification of the second hybrid (k x , y)-space data based on the relationship comprises:

determination of a phase correction associated with each pixel of the second hybrid (k x , y)-space data based on the relationship and the y-position of the pixel; and

for each pixel of the second hybrid (k x , y)-space data, application of the associated phase correction to the pixel to generate corrected second hybrid (k x , y)-space data.

20. A computing system according to claim 15 , the one or more processors to execute the program code to:

phase-correct the first frame of k-space data and the second frame of k-space data in the k x -direction.

Assignments (8)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 4, 2020
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: THE GENERAL HOSPITAL CORPORATION
Reel/Frame 052837/0163 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 16, 2020
From: HOGE, WILLIAM SCOTT; POLIMENI, JONATHAN RIZZO
To: THE GENERAL HOSPITAL CORPORATION
Reel/Frame 052416/0992 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 24, 2020
From: SIEMENS SHENZHEN MAGNETIC RESONANCE LTD.
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 052210/0250 →
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE/ASSIGNOR PREVIOUSLY RECORDED AT REEL: 051277 FRAME: 0012. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT . Recorded Feb 3, 2020
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 051778/0442 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 13, 2019
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 051277/0012 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 22, 2019
From: ZHOU, KUN; LIU, WEI
To: SIEMENS SHENZEN MAGNETIC RESONANCE LTD.
Reel/Frame 051088/0873 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2019
From: HÖLSCHER, UVO
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 050816/0376 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2019
From: CHANG, YULIN
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 050816/0242 →
Continuity (2)
Provisional Application 62831774 · Apr 10, 2019
Related Publication 20200326398A1 · Oct 15, 2020
Cited By (1)
US 12,704,576