Device and method of inhibiting endoleaks
A stent for placement in a blood vessel with a wall having an aneurysm including an endovascular graft having a first end, a second end, and a tubular body that is expandable and extends from the first end to the second end. The stent also includes a coagulation apparatus attached to the tubular body between the first and second ends. The coagulation apparatus has a frame and a coagulant attached to the frame. When the stent is deployed within the blood vessel, the tubular body extends across the aneurysm and expands at the first and second ends to seal against the wall of the blood vessel such that blood is channeled across the aneurysm through the tubular body such that a pocket of blood is defined external to the tubular body. The frame expands into the pocket to orient the coagulant therein and promote coagulation of blood within the pocket.
1. A stent for placement in a blood vessel with a wall having an aneurysm, the stent comprising:
an endovascular graft having a first end, a second end, and a tubular body that is expandable and extends from the first end to the second end; and
a coagulation apparatus attached to the tubular body of the endovascular graft between the first end and the second end, the coagulation apparatus having a frame and a coagulant attached to the frame, wherein the coagulant comprises fibrous material that defines a porous web within the coagulation apparatus by which the frame is circumferentially tethered to the tubular body; wherein the fibrous material is arranged in a plurality of overlapping tiers, each tier of the plurality of overlapping tiers comprising at least one fibrous strand oriented to define a network of pores within the porous web, wherein each tier of the plurality of overlapping tiers circumscribes the tubular body; and wherein the porous web spans a space defined between the frame and the tubular body; and
wherein, when the stent is deployed within the blood vessel, the tubular body extends across the aneurysm and is configured to expand at the first end and the second end to seal against the wall of the blood vessel such that blood is channeled across the aneurysm through the tubular body such that a pocket of blood is defined external to the tubular body, and wherein the frame is configured to expand into the pocket to orient the coagulant within the pocket and promote coagulation of the blood within the pocket.
2. The stent in accordance with claim 1 , wherein the tubular body comprises a cage and a cover attached to the cage, and wherein the cage is expandable to seal the tubular body against the wall of the blood vessel.
3. The stent in accordance with claim 2 , wherein the cover is fabricated from a substantially liquid-impermeable material.
4. The stent in accordance with claim 1 , wherein the fibrous material is coupled between the endovascular graft and the frame such that radial expansion of the frame relative to the endovascular graft is limited.
5. The stent in accordance with claim 1 , wherein the fibrous material is fabricated from thrombogenic material.
6. The stent in accordance with claim 1 , wherein the plurality of tiers are each spaced from each other along a length of the tubular body.
7. The stent in accordance with claim 1 , wherein the frame is fabricated from a shape memory alloy material.
8. The stent in accordance with claim 1 , wherein the coagulation apparatus is configured to deploy when an amount of force applied thereto is less than a predetermined threshold, and is configured to collapse when the amount of force applied thereto is greater than a predetermined threshold.
9. A method of inhibiting endoleaks in a blood vessel with a wall having an aneurysm, the method comprising:
inserting a stent within the blood vessel at a site of the aneurysm, wherein the stent includes an endovascular graft, having a first end, a second end, and a tubular body, and a coagulation apparatus attached to the tubular body of the endovascular graft between the first end and the second end, the coagulation apparatus having a frame and a coagulant attached to the frame, wherein the coagulant comprises fibrous material that defines a porous web within the coagulation apparatus by which the frame is circumferentially tethered to the tubular body; wherein the fibrous material is arranged in a plurality of overlapping tiers, each tier of the plurality of overlapping tiers comprising at least one fibrous strand oriented to define a network of pores within the porous web, wherein each tier of the plurality of overlapping tiers circumscribes the tubular body; and wherein the porous web spans a space defined between the frame and the tubular body; and
deploying the coagulation apparatus from a compressed state such that the frame expands into a pocket of blood, defined by the aneurysm, to orient the coagulant within the pocket and promote coagulation of the blood within the pocket.
10. The method in accordance with claim 9 , wherein inserting a stent comprises positioning the stent within the blood vessel such that the tubular body extends across the aneurysm, and wherein the tubular body is configured to expand at a first end and a second end thereof to seal against the wall of the blood vessel.
11. The method in accordance with claim 9 , wherein deploying the coagulation apparatus comprises unsheathing the coagulation apparatus.
12. The method in accordance with claim 9 , wherein deploying the coagulation apparatus is with a balloon-expandable platform.
13. A stent comprising:
an endovascular graft having a first end, a second end, and a tubular body that is expandable and extends from the first end to the second end; and
a coagulation apparatus attached to the tubular body of the endovascular graft between the first end and the second end, the coagulation apparatus having a frame and a coagulant attached to the frame, wherein the coagulant comprises fibrous material that defines a porous web within the coagulation apparatus by which the frame is circumferentially tethered to the tubular body; wherein the fibrous material is arranged in a plurality of overlapping tiers, each tier of the plurality of overlapping tiers comprising at least one fibrous strand oriented to define a network of pores within the porous web, wherein each tier of the plurality of overlapping tiers circumscribes the tubular body; and wherein the porous web spans a space defined between the frame and the tubular body.
14. The stent in accordance with claim 13 , wherein the tubular body comprises a cage and a cover attached to the cage, and wherein the cage is expandable to seal the tubular body against a wall of a blood vessel.
15. The stent in accordance with claim 14 , wherein the cover is fabricated from a substantially liquid-impermeable material.
16. The stent in accordance with claim 13 , wherein the coagulation apparatus extends circumferentially about the tubular body.
17. The stent in accordance with claim 13 , wherein the fibrous material is coupled between the endovascular graft and the frame such that radial expansion of the frame relative to the endovascular graft is limited.
18. The stent in accordance with claim 13 , wherein the fibrous material is fabricated from thrombogenic material.
19. The stent in accordance with claim 13 , wherein the plurality of tiers are each spaced from each other along a length of the tubular body.