IP Library › Granted Patent US 11,229,754
Granted Patent B2
US 11,229,754 · App. 16/630,988 · Granted Jan 25, 2022

Nebulizer and reservoir

Inventors: Joachim Carl Herbert Eicher (Ingelheim am Rhein, DE); Alfred Von Schuckmann (Kevelaer, DE)
Assignee: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
A61M11/007A61M15/005A61M15/009A61M15/0036A61M15/0073B05B11/0008B05B11/0038B05B11/00412B05B11/00442B05B11/00446B05B11/3035B05B11/3074B05B11/3081B05B11/3091B05B11/3095B29C65/02B29C66/1122B29C66/232B29C66/4326B65D83/0077A61M2205/07A61M2205/75A61M2205/8281B29L2031/7148
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Quick Facts
Patent No.
US 11,229,754
App. No.
16/630,988
Granted
Jan 25, 2022
Kind
B2
Abstract

A nebulizer for nebulizing a fluid and a reservoir with a fluid are proposed. The reservoir includes a collapsible bag with the fluid, where the bag extends in a circumferential direction within the housing part and wherein the reservoir is manually rotated for tensioning the nebulizer.

Claims (160)

1. A reservoir ( 3 ) for a nebulizer ( 1 ), the reservoir ( 3 ) comprising:

a collapsible bag ( 4 ) with multiple doses of a fluid ( 2 ) to be nebulized, and

a housing part ( 7 ) containing the collapsible bag ( 4 ),

wherein the collapsible bag ( 4 ) extends in a circumferential direction within the housing part ( 7 ) and/or is curved around a central axis (R) of the reservoir ( 3 ), and/or

wherein the reservoir ( 3 ) comprises a flexible fluid connection ( 5 ) and a connector ( 6 ) for fluidically connecting the collapsible bag ( 4 ) to the nebulizer ( 1 ).

2. The reservoir according to claim 1 , wherein at least one of:

the collapsible bag ( 4 ) comprises multiple compartments ( 4 A, 4 B, 4 C), and

the compartments ( 4 A, 4 B, 4 C) are at least essentially flat.

3. The reservoir according to claim 2 , wherein at least one of:

the compartments ( 4 A, 4 B, 4 C) are angled towards each other,

the compartments ( 4 A, 4 B, 4 C) are angled towards each other in a U-shaped manner and

the compartments ( 4 A, 4 B, 4 C) are angled towards each other such that the collapsible bag ( 4 ) at least partially surrounds at least one of the connector ( 6 ) and the central axis (R) of the reservoir ( 3 ).

4. The reservoir according to claim 2 , wherein at least one of:

the compartments ( 4 A, 4 B, 4 C) are fluidically connected to one another, and

the fluid connection ( 5 ) comprises or forms a joint outlet for the compartments ( 4 A, 4 B, 4 C).

5. The reservoir according to claim 1 , wherein the reservoir ( 3 ) comprises multiple tanks or bags ( 4 ).

6. The reservoir according to claim 2 , wherein at least one of:

the reservoir ( 3 ) comprises different fluids ( 2 A, 2 B, 2 C), each fluid ( 2 ) is contained in different compartments ( 4 A, 4 B, 4 C), and each fluid ( 2 ) is contained in different collapsible bags ( 4 ).

7. The reservoir according to claim 6 , wherein at least one of:

the reservoir ( 3 ) comprises a mixing chamber ( 36 ) for mixing the different fluids ( 2 A, 2 B, 2 C), and

the mixing chamber ( 36 ) mixes the different fluids ( 2 A, 2 B, 2 C) just before nebulization.

8. The reservoir according to claim 1 , wherein at least one of:

the collapsible bag ( 4 ) is at least essentially flat, and

an annular/circumferential extension of the collapsible bag ( 4 ) is larger than at least one of an axial extension of the collapsible bag ( 4 ), and an axial extension of the housing part ( 7 ).

9. The reservoir according to claim 1 , wherein at least one of:

the collapsible bag ( 4 ) is formed by a sheet ( 40 , 41 )

the collapsible bag ( 4 ) is formed by a welded sheet ( 40 , 41 ), and

the collapsible bag ( 4 ) is made of plastics.

10. The reservoir according to claim 1 , wherein the collapsible bag ( 4 ) is exchangeable.

11. The reservoir according to claim 1 , wherein at least one of:

the reservoir ( 3 ) comprises or forms a holding device ( 21 ) for at least one of holding and guiding the connector ( 6 ),

the housing part ( 7 ) comprises or forms a holding device ( 21 ) for at least one of holding and guiding the connector ( 6 ), and

the holding device of at least one of the reservoir ( 3 ) and the housing part ( 7 ) at least one of circumferentially, radially, and axially at least one of holds and guides the connector ( 6 ).

12. The reservoir according to claim 11 , wherein at least one of:

the holding device ( 21 ) holds the connector ( 6 ) in a delivery state of the reservoir ( 3 ) or before first use or until the reservoir ( 3 ) is connected to the nebulizer ( 1 ), and

the holding device ( 21 ) releases the connector ( 6 ) and/or allows a reciprocating movement of the connector ( 6 ) after the reservoir ( 3 ) or connector ( 6 ) has been connected to the nebulizer ( 1 ).

13. The reservoir according to claim 1 , wherein the flexible fluid connection ( 5 ) is formed by, or comprises, a flexible tube ( 5 A).

14. The reservoir according to claim 1 , wherein at least one of:

the fluid connection ( 5 ) is at least partially laminated into the collapsible bag ( 4 ),

a flexible tube ( 5 A) of the fluid connection ( 5 ) is at least partially laminated into the collapsible bag ( 4 ), and

an axial end of the flexible tube ( 5 A) of the fluid connection ( 5 ) is at least partially laminated into the collapsible bag ( 4 ).

15. The reservoir according to claim 1 , wherein at least one of:

the fluid connection ( 5 ) comprises a cover ( 5 B), and

the cover ( 5 B) is made of aluminium, and

the cover ( 5 B) is made of a same material as the collapsible bag ( 4 ).

16. The reservoir according to claim 15 , wherein the cover ( 5 B) of the fluid connection ( 5 ) and the collapsible bag ( 4 ) are formed integrally.

17. The reservoir according to claim 1 , wherein at least one of:

the collapsible bag ( 4 ) is immovable relative to the housing part ( 7 ),

the connector ( 6 ) is moveable in a reciprocating manner, relative to at least one of the collapsible bag ( 4 ) and the housing part ( 7 ),

the connector ( 6 ) is axially moveable relative to at least one of the collapsible bag ( 4 ) and the housing part ( 7 ), and

the connector ( 6 ) is axially moveable in a reciprocating manner relative to at least one of the collapsible bag ( 4 ) and the housing part ( 7 ).

18. The reservoir according to claim 1 , wherein at least one of:

the reservoir ( 3 ) comprises a pump device ( 39 ) for pressurizing the fluid ( 2 ) to help withdrawing the fluid ( 2 ) in doses, and

the pump device ( 39 ) temporarily pressurizes the fluid ( 2 ) to help withdrawing the fluid ( 2 ) in doses.

19. The reservoir according to claim 18 , wherein at least one of:

the pump device ( 39 ) is embodied as an air pump,

the pump device ( 39 ) is adapted to pressurize the fluid ( 2 ) contained in the collapsible bag ( 4 ), and

the pump device ( 39 ) is adapted to pressurize the fluid ( 2 ) contained in the collapsible bag ( 4 ) by pressurizing the air in at least one of the housing part ( 7 ) and a space ( 28 ) of the reservoir ( 3 ) containing the collapsible bag ( 4 ).

20. The reservoir according to claim 18 , wherein at least one of:

the pump device ( 39 ) comprises or forms a piston/cylinder arrangement,

the piston/cylinder arrangement helps in withdrawing the fluid ( 2 ) in doses from the collapsible bag ( 4 ),

the connector ( 6 ) comprises or forms a piston of the pump device ( 39 ), and

the housing part ( 7 ) comprises or forms a cylinder of the pump device ( 39 ).

21. The reservoir according to claim 18 , wherein at least one of:

the pump device ( 39 ) is embodied as a bellows in order to pressurize the fluid ( 2 ) contained therein, and

the pump device ( 39 ) comprises a compressible chamber ( 36 ) in order to pressurize the fluid ( 2 ) contained therein.

22. The reservoir according to claim 1 , wherein at least one of:

the reservoir ( 3 ) comprises a pressurizing device ( 50 ) for pressurizing the fluid ( 2 ),

the pressurizing device ( 50 ) pressurizes the fluid ( 2 ) within the collapsible bag ( 4 ),

the pressurizing device ( 50 ) includes a pressurizing spring for pressurizing the fluid ( 2 ), and

the pressurizing device ( 50 ) pressurizes the fluid ( 2 ) constantly and/or independently from a movement of the connector ( 6 ).

23. The reservoir according to claim 22 , wherein at least one of:

the pressurizing device ( 50 ) presses radially against the collapsible bag ( 4 ), and

the pressurizing device ( 50 ) presses radially against a flat side of the collapsible bag ( 4 ).

24. The reservoir according to claim 1 , wherein the reservoir ( 3 ) comprises an indicator device ( 51 ) for counting or indicating a number of uses performed or still possible with the reservoir ( 3 ).

25. The reservoir according to claim 24 , wherein the indicator device ( 51 ) comprises or forms a first axial end and/or a bottom ( 29 ) of the reservoir ( 3 ) and/or that the indicator device ( 51 ) is actuated/actuatable from a second axial end and/or a top of the reservoir ( 3 ).

26. The reservoir according to claim 24 , wherein the connector ( 6 ) comprises or forms the second axial end and/or the top of the reservoir ( 3 ).

27. The reservoir according to claim 24 , wherein the indicator device ( 51 ) is actuated by moving the connector ( 6 ) relative to the collapsible bag ( 4 ).

28. The reservoir according to claim 24 , wherein the indicator device ( 51 ) is directly and/or rigidly fixed to the housing part ( 7 ) of the reservoir ( 3 ).

29. The reservoir according to claim 24 , wherein at least one of:

the indicator device ( 51 ) comprises an indicator element ( 55 ) for indexing the indicator element ( 55 ),

the indicator element ( 55 ) is ring-shaped, and

the indicator device ( 51 ) comprises a reciprocatable actuation element ( 56 ) for indexing the indicator element ( 55 ).

30. The reservoir according to claim 29 , wherein at least one of:

the indicator device ( 51 ) comprises a transmission ( 57 ),

the actuation element ( 56 ) is mechanically coupled to the indicator element ( 55 ) via the transmission ( 57 ), and

a linear movement of the actuation element ( 56 ) is transformed to a rotation of the indicator element ( 55 ) via the transmission ( 57 ).

31. The reservoir according to claim 24 , wherein at least one of:

the connector ( 6 ) comprises or forms a driving part ( 60 ) for driving the indicator device ( 51 ), and

the driving part ( 60 ) operates to drive the actuation element ( 56 ) of the indicator device ( 51 ).

32. The reservoir according to claim 31 , wherein at least one of:

the reservoir ( 3 ) comprises or forms guidance for the connector ( 6 ),

the holding device ( 21 ) comprises or forms guidance for the connector ( 6 ),

the guidance is eccentrical linear, and

the guidance operates on the driving part ( 60 ).

33. The reservoir according to claim 32 , wherein at least one of:

the linear guidance is formed by a longitudinal groove in the housing part ( 7 ), and

the longitudinal groove is in the holding device ( 21 ) of the housing part ( 7 ).

34. The reservoir according to claim 1 , wherein at least one of:

the connector ( 6 ) is eccentrically arranged and/or guided within at least one of the reservoir ( 3 ), and the housing part ( 7 ), and

the central axis of the connector ( 6 ) is radially spaced apart from central axis (R) of at least one of the reservoir ( 3 ), and the housing part ( 7 ).

35. A nebulizer ( 1 ) for a fluid ( 2 ), comprising:

a reservoir ( 3 ) containing multiple doses of the fluid ( 2 ), and

a fluid pump ( 8 ) for withdrawing a dose of the fluid ( 2 ) from the reservoir ( 3 ) and pressurizing the respective dose for nebulization,

wherein the reservoir ( 3 ) comprises:

a tank or bag ( 4 ) with multiple doses of a fluid ( 2 ) to be nebulized, and

a housing part ( 7 ) containing the tank or bag ( 4 ),

wherein the tank or bag ( 4 ) extends in a circumferential direction within the housing part ( 7 ) and/or is curved around a central axis (R) of the reservoir ( 3 ), and/or

wherein the reservoir ( 3 ) comprises a flexible fluid connection ( 5 ) and a connector ( 6 ) for fluidically connecting the tank or bag ( 4 ) to the nebulizer ( 1 ).

36. A nebulizer ( 1 ) for a fluid ( 2 ), comprising:

a reservoir ( 3 ) containing multiple doses of the fluid ( 2 ), wherein the reservoir ( 3 ) comprises:

a tank or bag ( 4 ) with multiple doses of a fluid ( 2 ) to be nebulized, and

a housing part ( 7 ) containing the tank or bag ( 4 ),

wherein the tank or bag ( 4 ) extends in a circumferential direction within the housing part ( 7 ) and/or is curved around a central axis (R) of the reservoir ( 3 ), and/or

wherein the reservoir ( 3 ) comprises a flexible fluid connection ( 5 ) and a connector ( 6 ) for fluidically connecting the tank or bag ( 4 ) to the nebulizer ( 1 ); and

a fluid pump ( 8 ) for withdrawing a dose of the fluid ( 2 ) from the reservoir ( 3 ) and pressurizing the respective dose for nebulization,

wherein the reservoir ( 3 ) or a tank or bag ( 4 ) thereof is arranged at least partially around an energy store or drive of the nebulizer ( 1 ) for driving the fluid pump ( 8 ) and/or at least partially around the fluid pump ( 8 ) or its pump or pressure chamber ( 11 ).

37. The nebulizer according to claim 36 , wherein at least one of:

the fluid pump ( 8 ) comprises a reciprocating conveying element ( 9 ),

at least one of the reservoir ( 3 ) and the tank or bag ( 4 ), is held non-reciprocating by the nebulizer ( 1 ) and is fluidically connected or connectable via a fluid connection ( 5 ) with the conveying element ( 9 ), and

the fluid connection ( 5 ) is flexible.

38. The nebulizer according to claim 36 , wherein the tank or bag ( 4 ) comprises multiple compartments ( 4 A, 4 B, 4 C).

39. The nebulizer according to claim 38 , wherein the compartments ( 4 A, 4 B, 4 C) are angled towards each other.

40. The nebulizer according to claim 36 , wherein at least one of:

at least one of the tank or bag ( 4 ) and the compartments ( 4 A, 4 B, 4 C), is/are arranged in a U-shaped manner around at least one of the fluid pump ( 8 ), the pump or pressure chamber ( 11 ), and the energy store or drive of the nebulizer ( 1 ), and

at least one of the tank or bag ( 4 ) and the compartments ( 4 A, 4 B, 4 C), is/are arranged such that the tank or bag ( 4 ) at least partially surrounds the central axis (R) of the reservoir ( 3 ) and/or fluid pump ( 8 ).

41. The nebulizer according to claim 36 , wherein at least one of:

the central axis (R) of the reservoir ( 3 ) is spaced apart from the central axis (N) of at least one of the nebulizer ( 1 ) and the fluid pump ( 8 ), and

at least one of the fluid pump ( 8 ) and the energy store or drive is arranged eccentrically within the reservoir ( 3 ).

42. A nebulizer ( 1 ) for a fluid ( 2 ), comprising:

a reservoir ( 3 ) containing multiple doses of the fluid ( 2 ), wherein the reservoir ( 3 ) comprises:

a collapsible bag ( 4 ) with multiple doses of a fluid ( 2 ) to be nebulized, and

a housing part ( 7 ) containing the collapsible bag ( 4 ),

wherein the collapsible bag ( 4 ) extends in a circumferential direction within the housing part ( 7 ) and/or is curved around a central axis (R) of the reservoir ( 3 ), and/or

that the reservoir ( 3 ) comprises a flexible fluid connection ( 5 ) and a connector ( 6 ) for fluidically connecting the collapsible bag ( 4 ) to the nebulizer ( 1 ); and

a fluid pump ( 8 ) for withdrawing a dose of the fluid ( 2 ) from the reservoir ( 3 ) and pressurizing the respective dose for nebulization,

characterized in that the fluid pump ( 8 ) comprises a reciprocating conveying element ( 9 ), wherein the reservoir ( 3 ) is held non-reciprocating by the nebulizer ( 1 ) and fluidically connected or connectable via a preferably flexible fluid connection ( 5 ) with the conveying element ( 9 ).

43. The nebulizer according to claim 42 , wherein the reservoir ( 3 ) or the collapsible bag ( 4 ) thereof is arranged at least partially around a central axis (N) of the nebulizer ( 1 ), around the fluid pump ( 8 ) or its pump or pressure chamber ( 11 ) and/or around an energy store or drive of the nebulizer ( 1 ) for driving the fluid pump ( 8 ).

44. The nebulizer according to claim 42 wherein at least one of:

the reservoir ( 3 ) comprises the collapsible bag ( 4 ) containing the fluid ( 2 ), a connector ( 6 ) for fluidically connecting the collapsible bag ( 4 ) to the conveying element ( 9 ) and a housing part ( 7 ) containing the collapsible bag ( 4 ), and

the connector ( 6 ) is axially moveable relative to at least one of the collapsible bag ( 4 ) the housing part ( 7 ), and the conveying element ( 9 ).

45. The nebulizer according to claim 44 , wherein at least one of:

the housing part ( 7 ) is attached in a non-reciprocating manner to at least one of the nebulizer ( 1 ) and an inner part ( 17 ) of the nebulizer ( 1 ), and

the connector ( 6 ) is held in a reciprocating manner by at least one of the nebulizer ( 1 ) and a holder ( 14 ) of the nebulizer ( 1 ).

46. The nebulizer according to claim 44 , wherein at least one of:

the nebulizer ( 1 ) comprises a holder ( 14 ) for mechanically holding the connector ( 6 ), and

the holder ( 14 ) is rotatable and/or axially moveable together with the connector ( 6 ) and/or the conveying element ( 9 ).

47. The nebulizer according to claim 35 , wherein the reservoir ( 3 ) comprises an indicator device ( 51 ) for counting or indicating a number of uses performed or still possible with the reservoir ( 3 ).

48. The nebulizer according to claim 47 , wherein indicator device ( 51 ) comprises or forms an axial end and/or a bottom ( 29 ) of the nebulizer ( 1 ) or reservoir ( 3 ).

49. The nebulizer according to claim 47 , wherein at least one of:

the nebulizer ( 1 ) comprises a driving part ( 60 ) for driving the indicator device ( 51 ),

the driving part ( 60 ) is axially moveable, and

the driving part ( 60 ) is axially moveable together with the conveying element ( 9 ).

50. The nebulizer according to claim 49 , wherein the connector ( 6 ) or the holder ( 14 ) of the nebulizer ( 1 ) comprises or forms the driving part ( 60 ).

51. The nebulizer according to claim 35 , wherein the reservoir ( 3 ) comprises multiple compartments or bags ( 4 A, 4 B, 4 C) with different fluids ( 2 A, 2 B).

52. The nebulizer according to claim 35 , wherein at least one of:

the reservoir ( 3 ), nebulizer ( 1 ) or fluid pump ( 8 ) comprises a mixing chamber ( 36 ) for mixing different fluids ( 2 A, 2 B, 2 C), and

the mixing chamber ( 36 ) mixes the different fluids ( 2 A, 2 B, 2 C) just before nebulization.

53. The nebulizer according to claim 35 , wherein at least one of:

at least one of the reservoir ( 3 ) the housing part ( 7 ), the nebulizer ( 1 ), and an inner part ( 18 ) of the nebulizer ( 1 ), includes a retaining element ( 19 ) so that the reservoir ( 3 ) is attached to the nebulizer ( 1 ) by force-fit, form-fit and/or snapping.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2020
From: EICHER, JOACHIM
To: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
Reel/Frame 052022/0479 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2020
From: VON SCHUCKMANN, ALFRED
To: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Reel/Frame 052022/0495 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2020
From: BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG
To: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Reel/Frame 052022/0526 →
Priority Claims (2)
EP 17020315 · Jul 21, 2017 · regional
WO PCT/EP2018/069848 · Jul 20, 2018 · international
Continuity (1)
Related Publication 20200261666A1 · Aug 20, 2020
Cited By (1)
US 12,721,959