Spectrum modeling systems, methods, and devices for particle therapy treatment planning
View Patent ↗Systems, devices, and methods for non-Gaussian energy distribution modeling for treatment planning algorithms used in particle radiation therapy.
1. A treatment planning device comprising:
a processor configured to:
determine an energy distribution for one or more particle beams, or portions thereof, from a particle therapy system, using a non-Gaussian model; and
generate a treatment plan based on the determined energy distribution, the treatment plan including an irradiation plan and additional information,
wherein the non-Gaussian model comprises a combination of error functions, and
wherein the treatment planning device is configured to convert the additional information into instructions for the particle therapy system to effect the irradiation plan.
2. The treatment planning device of claim 1 , wherein the model is given by:
p
(
E
)
=
a
(
Erf
(
E
+
b
-
c
d
)
-
Erf
(
E
-
b
-
c
d
)
)
,
where p is the distribution of energy E, a is a normalization constant, b is a width of a profile half, c is a mean energy, and d is a parameter defining a slope of spectral boundaries.
3. The treatment planning device of claim 1 , wherein the model is given by:
p
(
E
)
=
a
(
Erf
(
E
+
b
-
c
d
)
-
Erf
(
E
-
b
2
-
c
d
2
)
)
,
where p is the distribution of energy E, a is a normalization constant, b and b 2 are widths of profile halves, c is a mean energy, and d and d 2 are parameters defining a slope of spectral higher and lower boundaries.
4. The treatment planning device of claim 1 , further configured to use the determined energy distribution to calculate a dose from the one or more particle beams, or portions thereof, within a medium.
5. The treatment planning device of claim 4 , wherein the calculating of the dose employs an analytical function or a stochastic algorithm.
6. A particle therapy system comprising:
a beam generation system for generating one or more particle beams;
a beam transport system for conveying the one or more particle beams from the beam generation system;
at least one treatment station for irradiating a medium/patient with one or more particle beams, the at least one treatment station being coupled to the beam transport system to receive the conveyed one or more particle beams, or portions thereof;
a treatment planning device that determines an irradiation plan for the medium/patient based on energy distribution of particles within said one or more particle beams, or portions thereof; and
a controller configured to control at least the beam transport system and the beam generation system to effect the irradiation plan,
wherein the treatment planning device is configured to determine the energy distribution based on a non-Gaussian model, and
wherein the non-Gaussian model comprises a combination of error functions.
7. The system of claim 6 , wherein the treatment planning device is configured to use the determined energy distribution to calculate a dose from the one or more particle beams, or portions thereof, within the medium/patient.
8. The system of claim 7 , wherein the calculating of the dose employs an analytical function or a stochastic algorithm.
9. The system of claim 6 , wherein the model is given by:
p
(
E
)
=
a
(
Erf
(
E
+
b
-
c
d
)
-
Erf
(
E
-
b
-
c
d
)
)
,
where p is the distribution of energy E, a is a normalization constant, b is a width of a profile half, c is a mean energy, and d is a parameter defining a slope of spectral boundaries.
10. The system of claim 6 , wherein the model is given by:
p
(
E
)
=
a
(
Erf
(
E
+
b
-
c
d
)
-
Erf
(
E
-
b
2
-
c
d
2
)
)
,
where p is the distribution of energy E, a is a normalization constant, b and b 2 are widths of profile halves, c is a mean energy, and d and d 2 are parameters defining a slope of spectral higher and lower boundaries.
11. The system of claim 6 , wherein the beam generation system comprises a cyclotron or a synchrotron.
12. The system of claim 6 , wherein the beam transport system comprises an energy analysis and selection system, and wherein the energy analysis and selection system comprises at least one of a degrader and an energy defining slit.