Small flexible liquid core catheter for laser ablation in body lumens and methods for use
Embodiments relate to the design and use of a low profile ablation catheter with a liquid core for use in laser ablation removal of arterial plaque blockages to restore blood flow.
1. A support catheter for use supporting a liquid core ablation catheter, comprising:
an inner tubular layer comprising a thin wall liner comprising a low friction material, a base layer of high durometer material disposed over the thin wall liner and an inner lumen with an inner diameter which is configured to accommodate passage of the liquid core ablation catheter;
a braided layer disposed over an outer surface of the inner tubular layer;
an outer layer covering the braided layer;
a total wall thickness of 0.005 inches or less; and
a torqueability, pushability and kink resistance sufficient to guide the liquid core ablation catheter with a low enough profile to advance through an opening generated by laser ablation of tissue with the liquid core ablation catheter.
2. The support catheter of claim 1 wherein the low friction material of the inner tubular layer comprises PTFE, a hybrid of PTFE or other low friction polymer suitable for sterilization.
3. The support catheter of claim 1 further comprising at least one radiopaque marker disposed near a distal end of the support catheter to visualize the position of the distal end of the support catheter in a patient's body lumen and a position of the support catheter with respect to the liquid core ablation catheter disposed within the support catheter.
4. The support catheter of claim 1 wherein a distal section of the support catheter comprises a straight longitudinal section.
5. The support catheter of claim 1 further comprising an angled distal section configured for proper positioning of a distal end of the liquid core ablation catheter disposed within the inner lumen of the inner tubular layer of the support catheter.
6. The support catheter of claim 1 further comprising an angled distal section configured to nutate a distal end of the liquid core ablation catheter disposed within and extending distally from the support catheter upon rotation of the support catheter about a longitudinal axis thereof.
7. The support catheter of claim 6 wherein the angled distal section has a length of 5 mm to 50 mm.
8. The support catheter of claim 6 wherein a discharge axis of the angled distal section forms an angle of 3 degrees to 10 degrees with respect to a longitudinal axis of the support catheter.
9. The support catheter of claim 1 wherein a distal section of the support catheter comprises a tapered distal section configured to align a distal end of the liquid core ablation catheter which is disposed within the inner lumen of the inner tubular layer of the support catheter away from a wall of a patient's body lumen.
10. The support catheter of claim 1 wherein the low friction material of the thin wall liner comprises polytetrafluoroethylene and the high durometer material of the base layer comprises polyimide.
11. The support catheter of claim 1 wherein the inner diameter of the inner lumen of the inner tubular layer is configured to accommodate passage of the liquid core ablation catheter with space therebetween sufficient for saline injection to flush blood and contrast fluid distal of the liquid core ablation catheter distal end.
12. A catheter system, comprising:
a liquid core ablation catheter having an outer diameter of 1 mm to 2.5 mm; and
a support catheter for use supporting the liquid core ablation catheter, the support catheter comprising:
an inner tubular layer comprising a thin wall liner comprising a low friction material, a base layer of high durometer material disposed over the thin wall liner and an inner lumen with an inner diameter which is configured to accommodate passage of the liquid core ablation catheter,
a braided layer disposed over an outer surface of the inner tubular layer,
an outer layer covering the braided layer,
a total wall thickness of 0.005 inches or less, and
a torqueability, pushability and kink resistance sufficient to guide the liquid core ablation catheter with a low enough profile to advance through an opening generated by laser ablation of tissue with the liquid core ablation catheter.
13. The support catheter of claim 1 wherein the low friction material of the thin wall liner comprises polytetrafluoroethylene and the high durometer material of the base layer comprises polyimide.
14. The catheter system of claim 12 wherein the inner diameter of the inner lumen of the inner tubular layer is configured to accommodate passage of the liquid core ablation catheter with space therebetween sufficient for saline injection to flush blood and contrast fluid distal of the liquid core ablation catheter distal end.