Specimen treatment and measurement system
The specimen treatment and measurement system 2000 according to the present invention is provided with: a movement stage 2300 having a plurality of treatment lanes for treating specimens in parallel; a consumables supply module 2100 for storing consumables for use in treatment of the specimens, and supplying the consumables to the movement stage 2300 ; a cartridge supply module 2500 for storing cartridges for use in treatment of the specimens, and supplying the cartridges to the movement stage 2300 ; and a stage transfer mechanism 2400 for transferring the movement stage 2400 to each module. The cartridge supply module 2500 has a plurality of cartridge cartons for accommodating the cartridges stacked on top of each other, and a push-out mechanism for pushing cartridges out of a cartridge carton to a supply position of the cartridge supply module 2500.
1. A specimen treatment system for executing treatments including extraction, amplification and measurement of nucleic acids for multiple specimens in parallel, the system comprising:
a stage rack provided with a plurality of treatment lanes for executing the treatments in parallel;
a treatment execution module for executing the treatments by loading the stage rack therein;
a consumable supply module including a consumable supply stage for storing specimens and consumables used for the treatments, and a pick-up unit with joint ends jointed with openings of the consumables for picking up the consumables from the consumable supply stage; and
a cartridge supply module for storing cartridges that are used for at least one of extraction, amplification and measurement and supplying the cartridges to the stage rack, the cartridge supply module including a cartridge supply stage supplying the cartridges, and a cartridge picker for picking up one of the plurality of cartridges; and
a stage rack transfer mechanism for transferring the stage rack to each module, the stage rack transfer mechanism including at least one arm holding the stage rack, at least one rail movably holding the arm, and a transfer motor transferring the arm,
wherein the stage rack is detachable or exchangeable with respect to the treatment execution module, the stage rack having the plurality of cartridges disposed in the plurality of treatment lanes at the cartridge supply module,
wherein the treatment execution module comprises a treatment stage, a treatment execution unit having a plurality of dispensing nozzles and provided on the treatment stage, and the treatment execution unit executing measurement, a stage rack installation section installing the stage rack on the treatment stage, and a stage rack installing mechanism having a moving motor moving the stage rack to the stage rack installation section.
2. The specimen treatment system according to claim 1 , wherein the treatment is a batch treatment that is performed for the multiple specimens at the same time.
3. The specimen treatment system according to claim 1 ,
further comprising a second treatment execution module which is the same as the treatment execution module,
wherein the consumable supply module is arranged between the treatment execution module and the second treatment execution module.
4. The specimen treatment system according to claim 1 , wherein the cartridge supply module comprises at least one cartridge storage container for storing the cartridges in a stack, and a cartridge supplying mechanism for supplying the cartridges from the cartridge storage container to a supply position in the cartridge supply module.
5. The specimen treatment system according to claim 4 , wherein the cartridge supplying mechanism supplies one cartridge in the bottommost row of the cartridges stacked in the cartridge storage container to the supply position.
6. The specimen treatment system according to claim 4 , wherein the cartridge storage container and/or the cartridges comprise an information storage medium for readably storing the information of the cartridges.
7. The specimen treatment system according to claim 6 , wherein the cartridge supply module comprises an information reading unit for reading cartridge information from the information storage medium.
8. The specimen treatment system according to claim 1 , further comprising a cartridge securing mechanism for securing each of the cartridges to the stage rack, wherein the cartridge securing mechanism comprises a pin, a pin support, and a moving mechanism of the pin support, and the each of the cartridges has a recessed portion inserting the pin.
9. The specimen treatment system according to claim 1 , wherein at least a part of each of the cartridges the cartridge comprises at least one prefilled well in which a solution used for the treatment, a reagent for extracting nucleic acids and/or a reagent for amplifying the nucleic acids is sealed in advance.
10. The specimen treatment system according to claim 1 , wherein the stage rack comprises rails for slidably loading the cartridges, and cartridge receiving ports for accessing the cartridges to the rails.
11. The specimen treatment system according to claim 1 , wherein the cartridges comprise a first cartridge and a second cartridge, where the first cartridge and the second cartridge are accommodated in one lane.