IP Library › Granted Patent US 11,352,329
Granted Patent B2
US 11,352,329 · App. 16/925,096 · Granted Jun 7, 2022

HIV protease inhibitors

Inventors: Zhenhong R. Cai (Palo Alto, CA); Aesop Cho (Mountain View, CA); Ana Zurisadai Gonzalez Buenrostro (San Mateo, CA); Xiaochun Han (San Jose, CA); Salman Y. Jabri (San Francisco, CA); Ryan McFadden (Foster City, CA); Yingmei Qi (Foster City, CA); Johannes Voigt (Cambridge, MA); Jie Xu (Foster City, CA); Lianhong Xu (Palo Alto, CA); Hong Yang (Fremont, CA)
Assignee: Gilead Sciences, Inc.
C07D247/00A61P31/18C07D233/88C07D401/10C07D401/14C07D403/10C07D403/14C07D405/14C07D413/10C07D413/14C07D417/10C07D417/14C07D471/04C07D487/04C07D491/107A61K45/06
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Quick Facts
Patent No.
US 11,352,329
App. No.
16/925,096
Granted
Jun 7, 2022
Kind
B2
Abstract

The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compounds of Formula I, therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS symptoms in a mammal using compounds of Formula I.

Claims (10)

1. A compound of the formula

or a pharmaceutically acceptable salt thereof.

2. A compound of the formula

or a pharmaceutically acceptable salt thereof.

3. A compound of the formula

or a pharmaceutically acceptable salt thereof.

4. A compound of the formula

or a pharmaceutically acceptable salt thereof.

5. A compound of the formula

or a pharmaceutically acceptable salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 4, 2022
From: CAI, ZHENHONG R.; CHO, AESOP; BUENROSTRO, ANA ZURISADAI GONZALEZ; HAN, XIAOCHUN; JABRI, SALMAN Y.; MCFADDEN, RYAN; QI, YINGMEI; VOIGT, JOHANNES; YANG, HONG; XU, JIE; XU, LIANHONG
To: GILEAD SCIENCES, INC.
Reel/Frame 059489/0832 →
Continuity (3)
Continuation 16158446 · Oct 12, 2018
Provisional Application 62572243 · Oct 13, 2017
Related Publication 20210078959A1 · Mar 18, 2021
Cited By (2)
US 12,275,742 US 12,630,560