IP Library › Granted Patent US 11,360,081
Granted Patent B2
US 11,360,081 · App. 17/029,892 · Granted Jun 14, 2022

Cell-based method for determining an activity of botulinum toxin

Inventors: Chee Gun Lee (Yongin-si, KR); Ji Hyun Oum (Seongnam-si, KR); Vijayakumar Ajay (Seoul, KR); Xiangai Gui (Suwon-si, KR)
Assignee: HUGEL INC.
G01N33/5058C07K16/1282C12N5/0618G01N33/5014C07K2317/565C12N2500/32C12N2500/36
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Quick Facts
Patent No.
US 11,360,081
App. No.
17/029,892
Granted
Jun 14, 2022
Kind
B2
Abstract

A new cell line and an antibody for determining the activity of botulinum toxin are disclosed. Also disclosed is a method of determining the activity of botulinum toxin using the cell line and/or the antibody.

Claims (2)

1. A N2-42F cell line (accession number: KCTC 13712BP).

2. A method for culturing the N2-42F cell line of claim 1 , comprising culturing cells of the N2-42F cell line in a culture medium, wherein the culture medium contains ganglioside GT1b trisodium salt (GT1b).

Priority Claims (3)
KR 10-2018-0150640 · Nov 29, 2018 · national
KR 10-2018-0150997 · Nov 29, 2018 · national
KR 10-2018-0159701 · Dec 12, 2018 · national
Continuity (2)
Division 16245415 · Jan 11, 2019
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